Mimicking the Secretory Action of a Gland by a Composite System Made of a pH-Responsive Surfactant-Based Hydrogel and a Dialysis Membrane

被引：6

作者：

Cesaretti, Alessio ^{[1
]}

Di Guida, Irene ^{[1
]}

Caldero-Rodriguez, Naishka E. ^{[1
,2
]}

Clementi, Catia ^{[1
]}

Germani, Raimondo ^{[1
]}

Gentili, Pier Luigi ^{[1
]}

机构：

[1] Univ Perugia, Dept Chem Biol & Biotechnol, Via Elce Sotto 8, I-06123 Perugia, Italy

[2] Univ Puerto Rico, Coll Nat Sci, Dept Chem, Rio Piedras Campus, San Juan, PR 00931 USA

来源：

ACS OMEGA | 2018年 / 3卷 / 12期

基金：

美国国家科学基金会;

关键词：

MOLECULAR ROBOTS; NEURON; UV; RADIATION;

D O I：

10.1021/acsomega.8b02940

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The hydrogel obtained by a zwitterionic N-oxide surfactant is proposed as the core of a pH-responsive artificial gland model. The viscosity and pH variations, induced by pulse additions of acid and base, are investigated by a pyridinium salt and alizarin red S, respectively. The artificial gland model is implemented by enclosing the gel within a dialysis membrane, and its secretory action is tested by monitoring the release of a fluorescent acridinium salt.

引用

页码：16777 / 16783

页数：7

共 24 条

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