Most natural rock slope failures result from long-term strength degradation. It is often hypothesized that glacial retreat leads to enhanced progressive damage accumulation in adjacent rock slopes, due to mechanical unloading and changes to the thermal and hydraulic boundary conditions. However, direct observations of subsurface processes in a rock slope subject to glacial retreat are rare. In this paper, we present the design, implementation, and performance of a new borehole monitoring system installed on a rock slope in fractured crystalline rock located beside the glacier tongue of the retreating Great Aletsch Glacier (Valais, Switzerland). The three vertical, 50 m deep boreholes were instrumented to continuously monitor groundwater pressure, temperature and deformation at high resolution, in order to investigate therrno-hydro-mechanical coupled slope processes that drive progressive rock mass damage. We show that the system is capable of measuring both reversible and irreversible displacements along single fractures at magnitudes ranging between 0.001 mm to >= 2 mm in the studied rock slope, and that it is often possible to identify drivers of these deformation signals. The transient subsurface temperature field shows clear indications of former ice occupation in form of cold temperatures preserved at depth and superimposed annual temperature cycles penetrating down to a depth of about 17 m. The variability of the pressure head in the slope is driven by annual snowmelt infiltration cycles, rainfall events, and the assumed connection to englacial water of the temperate glacier. The new and continuously growing dataset presented here will enable us to relate the changing boundary conditions caused by glacial retreat and fatigue from daily to annual thermal and hydraulic loading cycles to progressive rock mass weakening, which may ultimately result in rock slope failure. (C) 2020 The Authors. Published by Elsevier B.V.