Context > Chronic obstructive pulmonary disease (COPD) is a frequent and disabling disease but epidemiologic data remain fragmentary. Objective > The objective of this work was to bring together and describe the French epidemiologic data about COPD. Methods > This review of the literature was performed by querying the NLM PubMed database in French and in English with the key words "chronic obstructive pulmonary disease", "epidemiology", "mortality", and "France". The studies including French data were selected. Results > Four prevalence studies and one mortality study were identified. Prevalence was estimated between 1,0 and 11.1% in the general population. The mean mortality rote between 2000 and 2002 was 84.3/100 000 in men and 19.1/100 000 in women. Smoking is the best documented risk factor and a dose-response relationship has been established. The attributable risk fraction for occupational exposure is assessed at 15 to 20%. Discussion > Prevalence studies ore rare and do not always include objective measures of respiratory function. There ore no specific French data in populations of smokers. COPD is a mojor public health issue. The main risk factor is smoking but the risk fraction attributable to occupational exposure is substantial. Epidemiologic knowledge of COPD should advance as the results of studies and screening program for at-risk subjects currently underway as port of the national COPD plan become available.
机构:
Brigham & Womens Hosp, Channing Lab, Div Pulm & Crit Care, Dept Med, Boston, MA 02115 USABrigham & Womens Hosp, Channing Lab, Div Pulm & Crit Care, Dept Med, Boston, MA 02115 USA
机构:
Univ Calif San Francisco, Dept Med, Div Occupat & Environm Med, San Francisco, CA 94143 USAUniv Calif San Francisco, Dept Med, Div Occupat & Environm Med, San Francisco, CA 94143 USA
Blanc, P. D.
Balmes, J. R.
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机构:
Univ Calif San Francisco, Dept Med, Div Occupat & Environm Med, San Francisco, CA 94143 USAUniv Calif San Francisco, Dept Med, Div Occupat & Environm Med, San Francisco, CA 94143 USA
机构:
FAC MED COCHIN PORT ROYAL,INST PATHOL MOLEC,INSERM,U15,F-75674 PARIS,FRANCEFAC MED COCHIN PORT ROYAL,INST PATHOL MOLEC,INSERM,U15,F-75674 PARIS,FRANCE
LABIE, D
NOUVELLE REVUE FRANCAISE D HEMATOLOGIE,
1987,
29
(03):
: 157
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157