Mitochondrial Aldehyde Dehydrogenase 2 (ALDH2) Activator Potentiates Glucose-Stimulated Insulin Secretion and Prevents 4-HNE Induced Beta-Cell Apoptosis

被引：0

|

作者：

Chang, Tien Jyun

Liu, Meng Wei

Chuang, Lee Ming

机构：

来源：

DIABETES | 2017年 / 66卷

关键词：

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

2171-P

引用

收藏

页码：A569 / A569

页数：1

相关论文

共 23 条

[1] Insulin resistance causes increased beta-cell mass but defective glucose-stimulated insulin secretion in a murine model of type 2 diabetes
Asghar, Z
Yau, D
Chan, F
LeRoith, D
Chan, CB
Wheeler, MB
DIABETOLOGIA, 2006, 49 (01) : 90 - 99
[2] Insulin resistance causes increased beta-cell mass but defective glucose-stimulated insulin secretion in a murine model of type 2 diabetes
Z. Asghar
D. Yau
F. Chan
D. LeRoith
C. B. Chan
M. B. Wheeler
Diabetologia, 2006, 49 : 90 - 99
[3] Insulin resistance causes increased beta-cell mass but defective glucose-stimulated insulin secretion in a murine model of type 2 diabetes
Z. Asghar
D. Yau
F. Chan
D. LeRoith
C. B. Chan
M. B. Wheeler
Diabetologia, 2006, 49 (3) : 615 - 615
[4] BETA-CELL CYTOPLASMIC CA-2+ BALANCE AS A DETERMINANT FOR GLUCOSE-STIMULATED INSULIN RELEASE
HELLMAN, B
DIABETOLOGIA, 1985, 28 (08) : 494 - 501
[5] Aldehyde Dehydrogenase 2 (ALDH2) Obliterates Insulin Resistance-Induced Myocardial Contractile Dysfunction through Regulation of Mitochondrial Function
Hu, Nan
Zhang, Yingmei
Nunn, Jennifer M.
Ren, Jun
DIABETES, 2013, 62 : A7 - A7
[6] Inhibition of mitochondrial Na+-Ca2+ exchanger increases mitochondrial metabolism and potentiates glucose-stimulated insulin secretion in rat pancreatic islets
Lee, B
Miles, PD
Vargas, L
Luan, P
Glasco, S
Kushnareva, Y
Kornbrust, ES
Grako, KA
Wollheim, CB
Maechler, P
Olefsky, JM
Anderson, CM
DIABETES, 2003, 52 (04) : 965 - 973
[7] Mice with β-Cell-Specific Knockout of Mitochondrial Pyruvate Carrier 2 Exhibit Defects in Glucose-Stimulated Insulin Secretion
Mccommis, Kyle S.
Hodges, Wesley
Mcdonald, William G.
Colca, Jerry R.
Kletzien, Rolf F.
Remedi, Maria
Finck, Brian N.
DIABETES, 2015, 64 : A588 - A588
[8] The mitochondrial Ca2+ uniporter (MCUa) is required for glucose-stimulated mitochondrial Ca2+ uptake and insulin secretion in mouse pancreatic beta cells
Haythorne, E. A.
Martinez-Sanchez, A.
Rizzuto, R.
Rutter, G. A.
DIABETOLOGIA, 2017, 60 : S197 - S197
[9] HMB, lysine, and arginine: a combination of ingredients that potentiates the glucose-stimulated insulin secretion via ERK1/2 activation in pancreatic beta cells
Lopez-Pedrosa, J. M.
Manzano, M.
Salto, R.
Giron, M. D.
Bueno-Vargas, P.
Rueda, R.
DIABETOLOGIA, 2024, 67 : S266 - S266
[10] STIMULATED CA2+ INFLUX RAISES MITOCHONDRIAL FREE CA2+ TO SUPRAMICROMOLAR LEVELS IN A PANCREATIC BETA-CELL LINE - POSSIBLE ROLE IN GLUCOSE AND AGONIST-INDUCED INSULIN-SECRETION
RUTTER, GA
THELER, JM
MURGIA, M
WOLLHEIM, CB
POZZAN, T
RIZZUTO, R
JOURNAL OF BIOLOGICAL CHEMISTRY, 1993, 268 (30) : 22385 - 22390