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Prevention of hypoglycaemia in a patient with type Ib glycogen storage disease by an amylase (α-glucosidase) inhibitor
被引:4
|作者:
Ihara, K
[1
]
Kuromaru, R
[1
]
Ryu, A
[1
]
Fukushige, J
[1
]
Hara, T
[1
]
机构:
[1] Kyushu Univ, Fac Med, Dept Paediat, Higashi Ku, Fukuoka 8128582, Japan
关键词:
alpha-glucosidase inhibitor;
hypoglycaemia;
type Ib glycogen storage disease;
voglibose;
D O I:
10.1080/08035259850158362
中图分类号:
R72 [儿科学];
学科分类号:
100202 ;
摘要:
Patients with type Ib glycogen storage disease (GSD Ib) are susceptible to hypoglycaemic episodes. To determine whether an amylase (alpha-glucosidase) inhibitor, voglibose, can be useful in the control of hypoglycaemia, we tried it in a 14-y-old male with GSD Ib. Oral administration of voglibose prolonged the duration of normoglycaemia and reduced the incidence of hypoglycaemia attacks. These findings indicate that voglibose may be useful for preventing hypoglycaemia in GSD Ib patients.
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页码:595 / 598
页数:4
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