Magnetic-Field-Assisted Electrospinning of Aligned Straight and Wavy Polymeric Nanofibers

被引:196
|
作者
Liu, Yaqing [1 ,2 ]
Zhang, Xinping [3 ]
Xia, Younan [4 ]
Yang, Hong [1 ]
机构
[1] Univ Rochester, Dept Chem Engn, Rochester, NY 14627 USA
[2] N Univ China, Shanxi Res Ctr Engn Technol Polymer Composites, Taiyuan 030051, Peoples R China
[3] Univ Rochester, Ctr Musculoskeletal Res, Sch Med & Dent, Rochester, NY 14642 USA
[4] Washington Univ, Dept Biomed Engn, St Louis, MO 63130 USA
基金
美国国家卫生研究院;
关键词
SCAFFOLDS; FIBERS; ALIGNMENT; ARRAYS; COLLAGEN; CELLS;
D O I
10.1002/adma.200903870
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Aligned straight and wavy fibers of biodegradable poly(D,L-lactic-co-glycolic acid) (PLGA) are fabricated using a magnetic-field-assisted electrospinning method. PLGA fibrous matrices prepared by this method can guide the growth of pluripotent murine mesenchymal stem cells. While the stem cells on the randomly oriented fibers adapt pseudo-sphere-like shape, those on aligned fibers exhibit elongated morphology along the long axes (see figure).
引用
收藏
页码:2454 / +
页数:5
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