In vitro cytotoxic activity of Thai medicinal plants used traditionally to treat cancer

被引：201
|
作者：
Itharat, A
Houghton, PJ
Eno-Amooquaye, E
Burke, PJ
Sampson, JH
Raman, A
机构：
[1] Univ London Kings Coll, Dept Pharm, Pharmacognosy Res Labs, London SE1 9NN, England
[2] Prince Songkha Univ, Fac Pharmaceut Sci, Dept Pharmacognosy & Pharmaceut Bot, Hat Yai 90110, Songkhla, Thailand
[3] Charing Cross Hosp, Dept Med Oncol, London W6 8RF, England
来源：
JOURNAL OF ETHNOPHARMACOLOGY | 2004年 / 90卷 / 01期
关键词：
dioscorea; siphonodon; cytotoxicity test; SRB assay; Thai anticancer plants;
D O I：
10.1016/j.jep.2003.09.014
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
The SRB assay was used to test cytotoxicity against three human cancer cell lines and one normal cell line of I I Thai medicinal plant species used by traditional doctors in treating cancer patients. The extraction procedures used were similar to those practised by Thai traditional doctors (ethanolic and water extracts). Extracts were tested against the human large cell lung carcinoma cell line COR-L23, the human breast adenocarcinoma cell line MCF-7 and human colon adenocarcinoma cell line LS-174T and normal human keratinocytes SVK-14. The results showed that three plants; Dioscorea membranacea Pierre ex Prain & Burkill, Dioscorea birmanica Prain & Burkill (Dioscoreaceae) and Siphonodon celastrineus Griff. (Celastraceae), exhibited high cytotoxic activity showing a certain degree of selectivity against the different cell types. (C) 2003 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码：33 / 38
页数：6
相关论文
共 50 条
  • [1] A Review On: Cytotoxic Activity of Indian Medicinal Plants Used Traditionally
    Dash, Sribatsa Lanchhana
    Mishra, Sagar Kumar
    Mohapatra, Ranjit
    Katiyar, Arpit
    [J]. RESEARCH JOURNAL OF PHARMACEUTICAL BIOLOGICAL AND CHEMICAL SCIENCES, 2018, 9 (02): : 200 - 209
  • [2] Investigation of some Thai medicinal plants used to treat cancer
    Techatanawat, I.
    Houghton, P. J.
    Steventon, G. B.
    Hylands, P. J.
    [J]. JOURNAL OF PHARMACY AND PHARMACOLOGY, 2004, 56 : S5 - S5
  • [3] In vitro antimycobacterial and cytotoxic data on medicinal plants used to treat tuberculosis
    Nguta, Joseph M.
    Appiah-Opong, Regina
    Nyarko, Alexander K.
    Yeboah-Manu, Dorothy
    Addo, Phyllis G. A.
    Otchere, Isaac D.
    Kissi-Twum, Abena
    [J]. DATA IN BRIEF, 2016, 7 : 1124 - 1130
  • [4] Traditionally used Thai medicinal plants: In vitro anti-inflammatory, anticancer and antioxidant activities
    Siriwatanametanon, Nisarat
    Fiebich, Bernd L.
    Efferth, Thomas
    Prieto, Jose M.
    Heinrich, Michael
    [J]. JOURNAL OF ETHNOPHARMACOLOGY, 2010, 130 (02) : 196 - 207
  • [5] Antimycobacterial activity of selected medicinal plants traditionally used in Sudan to treat infectious diseases
    Abuzeid, Nadir
    Kalsum, Sadaf
    Koshy, Richin John
    Larsson, Marie
    Glader, Mikaela
    Andersson, Henrik
    Raffetseder, Johanna
    Pienaar, Elsje
    Eklund, Daniel
    Alhassan, Muddathir S.
    AlGadir, Haidar A.
    Koko, Waleed S.
    Schon, Thomas
    Mesaik, M. Ahmed
    Abdalla, Omer M.
    Khalid, Asaad
    Lerm, Maria
    [J]. JOURNAL OF ETHNOPHARMACOLOGY, 2014, 157 : 134 - 139
  • [6] Review on antibacterial activity of Himalayan medicinal plants traditionally used to treat pneumonia and tuberculosis
    Adnan, Muhammad
    Ali, Shandana
    Sheikh, Khushboo
    Amber, Rahila
    [J]. JOURNAL OF PHARMACY AND PHARMACOLOGY, 2019, 71 (11) : 1599 - 1625
  • [7] In-vitro Antioxidant Activity of Eight Traditionally Used Indian Medicinal Plants
    Nair, Sujith S.
    Mathew, Molly
    Sreena, K.
    [J]. INTERNATIONAL JOURNAL OF PHARMACEUTICAL AND PHYTOPHARMACOLOGICAL RESEARCH, 2012, 2 (02): : 75 - 78
  • [8] In Vitro Cytotoxic Activity of Methanol Extracts of Selected Medicinal Plants Traditionally Used in Mexico against Human Hepatocellular Carcinoma
    Elizondo-Luevano, Joel H.
    Gomez-Flores, Ricardo
    Verde-Star, Maria J.
    Tamez-Guerra, Patricia
    Romo-Saenz, Cesar, I
    Chavez-Montes, Abelardo
    Rodriguez-Garza, Nancy E.
    Quintanilla-Licea, Ramiro
    [J]. PLANTS-BASEL, 2022, 11 (21):
  • [9] Plants used traditionally to treat malaria in Brazil: the archives of Flora Medicinal
    Alexandros S Botsaris
    [J]. Journal of Ethnobiology and Ethnomedicine, 3
  • [10] A review on antiviral activity of the Himalayan medicinal plants traditionally used to treat bronchitis and related symptoms
    Amber, Rahila
    Adnan, Muhammad
    Tariq, Akash
    Mussarat, Sakina
    [J]. JOURNAL OF PHARMACY AND PHARMACOLOGY, 2017, 69 (02) : 109 - 122
12345