Naproxen derivatives: Synthesis, reactions, and biological applications

被引:32
|
作者
Ammar, Y. A. [1 ]
Salem, M. A. [1 ,2 ]
Fayed, Eman A. [3 ]
Helal, M. H. [1 ,4 ]
El-Gaby, M. S. A. [5 ]
Thabet, H. Kh. [1 ,4 ]
机构
[1] Al Azhar Univ, Dept Chem, Fac Sci, Nasr City 11284, Cairo, Egypt
[2] King Khalid Univ, Fac Arts & Sci, Dept Chem, Mohail Assir, Saudi Arabia
[3] Al Azhar Univ, Fac Pharm Girls, Dept Organ Chem, Cairo, Egypt
[4] Northern Border Univ, Fac Arts & Sci, Dept Chem, Rafha, Saudi Arabia
[5] Al Azhar Univ, Dept Chem, Fac Sci, Assiut, Egypt
关键词
Amidation; anti-inflammatory; antioxidant; antitumor; antiviral; esterification; naproxen; 2-ARYLPROPIONIC ACIDS; ANTIINFLAMMATORY ACTIVITY; ASYMMETRIC-SYNTHESIS; AMIDE DERIVATIVES; ANALOGS; DISCOVERY; IBUPROFEN; PRODRUGS; BEARING;
D O I
10.1080/00397911.2017.1328066
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
This review describes the synthesis and reactions of naproxen derivatives and highlights the effects of compounds containing the naproxen moiety in important biological applications.
引用
收藏
页码:1341 / 1367
页数:27
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