Analysis of skin tissues spatial fluorescence distribution by the Monte Carlo simulation

被引：50

作者：

Churmakov, DY ^{[1
]}

Meglinski, IV

Piletsky, SA

Greenhalgh, DA

机构：

[1] Cranfield Univ, Sch Engn, Cranfield MK43 0AL, Beds, England

[2] Cranfield Univ, Inst Biosci & Technol, Silsoe MK45 4DT, England

来源：

JOURNAL OF PHYSICS D-APPLIED PHYSICS | 2003年 / 36卷 / 14期

关键词：

D O I：

10.1088/0022-3727/36/14/311

中图分类号：

O59 [应用物理学];

学科分类号：

摘要：

A novel Monte Carlo technique of simulation of spatial fluorescence distribution within the human skin is presented. The computational model of skin takes into account the spatial distribution of fluorophores, which would arise due to the structure of collagen fibres, compared to the epidermis and stratum corneum where the distribution of fluorophores is assumed to be homogeneous. The results of simulation suggest that distribution of auto-fluorescence is significantly suppressed in the near-infrared spectral region, whereas the spatial distribution of fluorescence sources within a sensor layer embedded in the epidermis is localized at an 'effective' depth.

引用

页码：1722 / 1728

页数：7

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