Photodynamic Therapy (PDT) to treat a chronic skin wound in a dog

被引：1

作者：

Hage, Raduan ^{[1
]}

Plapler, Helio ^{[1
]}

Bitar, Renata Andrade ^{[2
]}

机构：

[1] Univ Fed Sao Paulo, Operat Tech & Expt Surg Div, Dept Surg, Sao Paulo, Brazil

[2] Univ Fed Sao Paulo, Plast Surg & Univ Vale Paraiba, Lab Espectroscopia Vibrac Biomed IP&D, Sao Paulo, Brazil

来源：

OPTICAL METHODS FOR TUMOR TREATMENT AND DETECTION: MECHANISMS AND TECHNIQUES IN PHOTODYNAMIC THERAPY XVII | 2008年 / 6845卷

关键词：

photodynamic therapy; wound repair; methylene blue; dog;

D O I：

10.1117/12.761679

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 ;

摘要：

Photodynamic Therapy (PDT) is an emerging and promising therapeutic modality for treatment of a wide variety of malignant and nononcologic tumors, as well as in the treatment of infected skin ulcers. This study evaluated the effectiveness of the PDT to treat a chronic skin wound that had been already subjected to several clinical and surgical type treatments in a dog. The animal with an infected chronic skin wound with 8 cm diameter in the left leg received an injection of an aqueous solution of 1% methylene blue (MB) with 2% lidocaine into the lesion. After MB injection the wound was irradiated using a LED (LED-VET MMOptics(R)) with a wavelength between 600 and 700 nm, 2 cm diameter circular light beam, of 150 mW of power, light dose of 50 j/cm(2). After 3 and 6 weeks PDT was repeated and the wound was re-evaluated. Complete healing was achieved 10 weeks after the first procedure.

引用

页数：6

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