Management and Outcomes of Cardiogenic Shock in Cardiac ICUs With Versus Without Shock Teams

被引:94
|
作者
Papolos, Alexander I. [1 ]
Kenigsberg, Benjamin B. [1 ]
Berg, David D. [2 ]
Alviar, Carlos L. [3 ]
Bohula, Erin [2 ]
Burke, James A. [4 ]
Carnicelli, Anthony P.
Chaudhry, Sunit-Preet [6 ]
Drakos, Stavros [7 ]
Gerber, Daniel A. [8 ]
Guo, Jianping [2 ]
Horowitz, James M. [5 ]
Katz, Jason N. [5 ]
Keeley, Ellen C. [9 ]
Metkus, Thomas S. [10 ]
Nativi-Nicolau, Jose [7 ]
Snell, Jeffrey R. [11 ]
Sinha, Shashank S. [12 ]
Tymchak, Wayne J. [13 ]
Van Diepen, Sean [13 ]
Morrow, David A. [2 ]
Barnett, Christopher F. [1 ]
机构
[1] MedStar Washington Hosp Ctr, Dept Cardiol & Crit Care, Washington, DC USA
[2] Brigham & Womens Hosp, Cardiovasc Div, Dept Med, BTIMI Study Grp, Boston, MA USA
[3] NYU, Sch Med, Leon H Charney Div Cardiol, New York, NY USA
[4] Lehigh Valley Heart Inst, Allentown, PA USA
[5] Duke Univ Hosp, Dept Med, Durham, NC USA
[6] St Vincent Heart Ctr, Dept Med, Indianapolis, IN USA
[7] Univ Utah, Dept Med, Div Cardiovas Med, Salt Lake City, UT USA
[8] Stanford Univ, Sch Med, Dept Med, Stanford, CA USA
[9] Univ Florida, Dept Med, Gainesville, FL USA
[10] Johns Hopkins Univ, Sch Med, Dept Med, Baltimore, MD USA
[11] Rush Univ, Med Ctr, Div Cardiol, Dept Internal Med, Chicago, IL USA
[12] Inova Heart & Vasc Inst, Inova Fairfax Med Ctr, Falls Church, VA USA
[13] Univ Alberta, Dept Crit Care Med, Div Cardiol, Dept Med, Edmonton, AB, Canada
关键词
cardiac intensive care unit; cardiogenic shock; mechanical circulatory support; pulmonary artery catheter; shock team; ACUTE MYOCARDIAL-INFARCTION; MECHANICAL CIRCULATORY SUPPORT; HEART-FAILURE; SURVIVAL; CARE;
D O I
10.1016/j.jacc.2021.07.044
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
BACKGROUND Single-center studies suggest that implementation of multidisciplinary cardiogenic shock (CS) teams is associated with improved CS survival. OBJECTIVES The aim was to characterize practice patterns and outcomes in the management of CS across multiple centers with versus without shock teams. METHODS The Critical Care Cardiology Trials Network is a multicenter network of cardiac intensive care units (CICUs) in North America. All consecutive medical admissions to each CICU (n = 24) were captured during annual 2-month collection periods (2017-2019; n = 6,872). Shock management and CICU mortality among centers with versus without shock teams were compared using inverse probability weighting. RESULTS Ten of the 24 centers had shock teams. Among 1,242 CS admissions, 44% were at shock team centers. The groups were well-balanced with respect to demographics, shock etiology, Sequential Organ Failure Assessment score, biochemical markers of end organ dysfunction, and invasive hemodynamics. Centers with shock teams used more pul-monary artery catheters (60% vs 49%; adjusted odds ratio [OR]: 1.86; 95% CI: 1.47-2.35; P < 0.001), less overall mechanical circulatory support (MCS) (35% vs 43%; adjusted OR: 0.74; 95% CI: 0.59-0.95; P = 0.016), and more advanced types of MCS (53% vs 43% of all MCS; adjusted OR: 1.73; 95% CI: 1.19-2.51; P = 0.005) rather than intra-aortic balloon pumps. The presence of a shock team was independently associated with lower CICU mortality (23% vs 29%; adjusted OR: 0.72; 95% CI: 0.55-0.94; P = 0.016). CONCLUSIONS In this multicenter observational study, centers with shock teams were more likely to obtain invasive hemodynamics, use advanced types of MCS, and have lower risk-adjusted mortality. A standardized multidisciplinary shock team approach may improve outcomes in CS. (J Am Coll Cardiol 2021;78:1309-1317) (c) 2021 by the American College of Cardiology Foundation.
引用
收藏
页码:1309 / 1317
页数:9
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