Chemotactic responses of tunicate (Urochordata, Ascidiacea) hemocytes in vitro

被引：21
|
作者：
Raftos, DA [1 ]
Stillman, DL
Cooper, EL
机构：
[1] Macquarie Univ, Sch Biol Sci, N Ryde, NSW 2109, Australia
[2] Univ Calif Los Angeles, Sch Med, Dept Anat & Cell Biol, Los Angeles, CA 90024 USA
来源：
JOURNAL OF INVERTEBRATE PATHOLOGY | 1998年 / 72卷 / 01期
基金：
澳大利亚研究理事会; 美国国家科学基金会;
关键词：
tunicate; ascidian; chemotaxis; chemoattraction; chemokinesis;
D O I：
10.1006/jipa.1998.4760
中图分类号：
Q95 [动物学];
学科分类号：
071002 ;
摘要：
A number of molecules were found to alter the motility of tunicate hemocytes. Bacterial lipopolysaccharide (LPS) significantly enhanced cell mobility relative to non-stimulated controls. Responses to LPS mere not directional and so represented chemokinesis. In contrast, checkerboard analyses indicated that two tunicate hemolymph proteins, tunIL1-alpha and -beta, stimulated truly directional chemotaxis by hemocytes. The data suggest that tunIL1 proteins may contribute to defense by altering the localization of immunocompetent cells. (C) 1998 Academic Press.
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页码：44 / 49
页数：6
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