Kinetics of irreversible adsorption of deformable proteins

被引：20
|
作者：
Zhdanov, VP [1 ]
Kasemo, B
机构：
[1] Chalmers Univ Technol, Dept Appl Phys, S-41296 Gothenburg, Sweden
[2] Russian Acad Sci, Boreskov Inst Catalysis, Novosibirsk 630090, Russia
来源：
JOURNAL OF CHEMICAL PHYSICS | 1998年 / 109卷 / 15期
关键词：
D O I：
10.1063/1.477296
中图分类号：
O64 [物理化学（理论化学）、化学物理学];
学科分类号：
070304 ; 081704 ;
摘要：
Employing the Monte Carlo technique, we study the kinetics of random sequential adsorption of proteins in the case when this process is complicated by denaturation of proteins. Adsorbed denatured proteins are considered to be deformable, i.e., their shape may relax during adsorption of newly arriving proteins or denaturation of other adsorbed proteins. Using realistic values of the model parameters, we show that this effect may influence the late stage of the protein adsorption kinetics. (C) 1998 American Institute of Physics. [S0021-9606(98)51239-1].
引用
收藏
页码：6497 / 6501
页数：5
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