Novel surgical concept in antireflux surgery: Long-term outcomes comparing 3 different laparoscopic approaches

被引:6
|
作者
Mucio, Moreno [1 ,3 ]
Rojano, Martin [3 ]
Jesus Herrera, Jose [3 ]
Angel Valdovinos, Miguel [2 ]
Angel Cordova, J. [3 ]
Bravo, Carlos [3 ]
Dominguez, Luis [3 ]
Sanchez, Oscar [1 ]
机构
[1] Natl Inst Nutr & Med Sci Salvador Zubiran, GEA Hosp, Mexico City, DF, Mexico
[2] Natl Inst Nutr & Med Sci Salvador Zubiran, Dept Gastroenterol, Mexico City, DF, Mexico
[3] Natl Inst Nutr & Med Sci Salvador Zubiran, Dept Endoscop Surg, Mexico City, DF, Mexico
关键词
GASTROESOPHAGEAL-REFLUX DISEASE; FUNDOPLICATION; NISSEN; REPAIR; REINTERVENTION; COMPLICATIONS; OPERATIONS; GASTROPEXY; HERNIA; GERD;
D O I
10.1016/j.surg.2011.06.024
中图分类号
R61 [外科手术学];
学科分类号
摘要
Background. The Nissen fundoplication procedure is the most widely used type of antireflux surgery. The results are not always as good as expected, and several modifications to the original technique have been proposed. Long-term effectiveness studies comparing different techniques of antireflux surgery are limited. Our group developed a new concept in antireflux surgery (complete fixed "nondeformable" fundoplication) in order to improve its outcome; we present the long-term comparative results of this novel concept/technique. Methods. Overall, 512 patients were included in the study and assigned into 1 of 3 fundoplications groups: partial (131), Nissen (133), and fixed "nondeformable" (121). We compared the groups with each other and with a group who chose to receive medical treatment (MT) (127). All patients underwent clinical evaluation, upper gastrointestinal endoscopy, esophageal manometry, 24-hour esophageal pH monitoring, and the SF-36 health status survey prior to operation and at 1, 5, 10, and 15 years of follow-up. Results. At the 15-year follow-up, we were able to complete the protocol in 319 patients: 103 patients from the partial group, 102 patients from the Nissen group, 97 patients from the fixed "nondeformable" group, and 17 patients from the medical treatment group. A lower prevalence of erosive gastroesophageal reflux disease (GERD) was observed in the fixed "nondeformable" group (7.20%) versus 21.56% for Nissen, 39.80% for partial, and 47.05 % for MT (P < .01). Lower esophageal sphincter (LES) pressure and LES length were more constant in the fixed "nondeformable" group (14.7 mm Hg/2.2 cm) compared with the Nissen (9 mm Hg/0.7 cm), partial (7 mm Hg/2 cm), and MT (5.64 mm Hg/1.3 cm) groups (P < .01). Reflux recurrence was observed in 168 patients (13 in fixed "nondeformable," 41 in Nissen, and 98 in partial (P < .01). Conclusion. The complete fixed "nondeformable" fundoplication showed best results in studied parameters and had a lower long-term recurrence compared with Nissen and partial techniques. (Surgery 2012;151:84-93.)
引用
收藏
页码:84 / 93
页数:10
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