Characteristics and patterns of care of endometrial cancer before and during COVID-19 pandemic

被引：12

作者：

Bogani, Giorgio ^{[1
]}

Scambia, Giovanni ^{[2
]}

Cimmino, Chiara ^{[3
]}

Fanfani, Francesco ^{[2
]}

Costantini, Barbara ^{[2
]}

Loverro, Matteo ^{[2
]}

Ferrandina, Gabriella ^{[2
]}

Landoni, Fabio ^{[4
]}

Bazzurini, Luca ^{[4
]}

Grassi, Tommaso ^{[4
]}

Vitobello, Domenico ^{[5
]}

Siesto, Gabriele ^{[5
]}

Perrone, Anna Myriam ^{[6
]}

Zanagnolo, Vanna ^{[7
]}

De Iaco, Pierandrea ^{[6
]}

Multinu, Francesco ^{[7
]}

Ghezzi, Fabio ^{[3
]}

Casarin, Jvan ^{[3
]}

Capozzi, Vito A. ^{[8
]}

Zupi, Errico ^{[9
]}

Centini, Gabriele ^{[9
]}

Pellegrino, Antonio ^{[10
]}

Corso, Silvia ^{[10
]}

Stevenazzi, Guido ^{[11
]}

Montoli, Serena ^{[11
]}

Boschi, Anna Chiara ^{[12
]}

Comerci, Giuseppe ^{[12
]}

Greco, Pantaleo ^{[13
]}

Martinello, Ruby ^{[13
]}

Sopracordevole, Francesco ^{[14
]}

Giorda, Giorgio ^{[14
]}

Simoncini, Tommaso ^{[15
]}

Caretto, Marta ^{[15
]}

Sartori, Enrico ^{[16
]}

Ferrari, Federico ^{[16
]}

Cianci, Antonio ^{[17
]}

Sarpietro, Giuseppe ^{[17
]}

Matarazzo, Maria Grazia ^{[17
]}

Zullo, Fulvio ^{[18
]}

Bifulco, Giuseppe ^{[18
]}

Morelli, Michele ^{[19
]}

Ferrero, Annamaria ^{[20
]}

Biglia, Nicoletta ^{[20
]}

Barra, Fabio ^{[21
]}

Ferrero, Simone ^{[21
]}

Maggiore, Umberto Leone Roberti ^{[1
]}

Cianci, Stefano ^{[22
]}

Chiantera, Vito ^{[23
]}

Ercoli, Alfredo ^{[22
]}

Sozzi, Giulio ^{[23
]}

机构：

[1] Fdn IRCCS Ist Nazl Tumori Milano, Gynecol Oncol Unit, Via Giacomo Venezian 1, I-20133 Milan, Italy

[2] Fdn Policlin Univ A Gemelli IRCCS, Gynecol Oncol Unit, Rome, Italy

[3] Univ Insubria, F Ponte Hosp, Dept Obstet & Gynaecol, Varese, Italy

[4] San Gerardo Hosp, Dept Obstet & Gynaecol, Monza, Italy

[5] Humanitas Clin & Res Ctr IRCCS, Unit Gynecol, Humanitas Canc Ctr, Milan, Italy

[6] AOU S Orsola Malpighi, Unit Gynecol, Bologna, Italy

[7] European Inst Oncol IRCCS, Dept Gynecol Oncol, IEO, Milan, Italy

[8] Univ Parma, Dept Obstet & Gynaecol, Parma, Italy

[9] Univ Siena, Dept Obstet & Gynaecol, Siena, Italy

[10] ASST Lecco Osped Alessandro Manzoni, Dept Obstet & Gynaecol, Lecce, Italy

[11] Legnano Milan Hosp, Dept Obstet & Gynaecol, ASST OVEST MI, Legnano, Italy

[12] Osped Santa Maria Croci, Dept Obstet & Gynaecol, AUSL Romagna, Ravenna, Italy

[13] Univ Ferrara, Dipartimento Sci Med, Clin Ostetr & Ginecol, Ferarra, Italy

[14] Natl Canc Inst, Gynecol Oncol Unit, Ctr Riferimento Oncol, Aviano, Italy

[15] Univ Pisa, Div Obstet & Gynecol, Dept Clin & Expt Med, Pisa, Italy

[16] Univ Brescia, Dept Clin & Expt Sci, Brescia, Italy

[17] Univ Catania, Dept Gen Surg & Med Surg Specialties, Gynecol Clin, Catania, Italy

[18] Azienda Osped Univ Federico II, Dept Obstet & Gynaecol, Naples, Italy

[19] AO SS Annunziata, Dept Obstet & Gynaecol, Cosenza, Italy

[20] Mauriziano Hosp, Acad Dept Obstet & Gynecol, Turin, Italy

[21] IRCCS Osped Policlin San Martino, Acad Unit Obstet & Gynecol, Genoa, Italy

[22] Univ Messina, Univ Hosp G Martino, Dept Human Pathol Adulthood & Childhood G Barresi, Unit Gynecol & Obstet, Messina, Italy

[23] Univ Palermo, Dept Gynecol Oncol, Palermo, Italy

[24] AOR San Carlo, Dept Obstet & Gynaecol, Potenza, Italy

[25] ARNAS Garibaldi Catania, Dept Obstet & Gynaecol, Catania, Italy

[26] ASO Santa Croce & Carle, Dept Obstet & Gynaecol, Cuneo, Italy

[27] Sapienza Univ Rome, Dept Maternal & Child Hlth & Urol Sci, Policlin Umberto 1, Rome, Italy

[28] Univ Hosp Udine, Dept Maternal & Child Hlth, Udine, Italy

[29] IRCCS San Raffaele Hosp, Dept Obstet & Gynaecol, Milan, Italy

[30] Campus Bio Medico Univ Rome, Dept Obstet & Gynecol, Rome, Italy

[31] Sacred Heart Hosp Negrar, Int Sch Surg Anat, Dept Obstet & Gynecol, Gynecol Oncol & Minimally Invas Pelv Surg, Verona, Italy

[32] IRCCS Fdn Policlin San Matteo, Dept Obstet & Gynecol, Pavia, Italy

[33] Univ Pavia, Pavia, Italy

[34] S Antonio Abate Hosp, Dept Obstet & Gynecol, Trapani, Italy

[35] Univ Palermo, Dept Hlth Promot Mother & Child Care, Internal Med & Med Specialties PROMISE, Palermo, Italy

[36] Hop Beauregard, AUSL Vallee Aoste, Dept Gynecol, Aosta, Italy

[37] Hop Beauregard, AUSL Vallee Aoste, Dept Obstet, Aosta, Italy

[38] Univ Bologna, IRCCS Azienda Osped Univ Bologna, Div Gynaecol & Human Reprod Physiopathol, Dept Med & Surg Sci DIMEC,S Orsola Hosp, Bologna, Italy

[39] Ctr Adv Endoscop Gynecol Surg, Endoscop Malzoni, Avellino, Italy

[40] Ente Ospedaliero Osped Galliera, Dept Obstet & Gynaecol, Genoa, Italy

[41] Osped Treviso, Dept Obstet & Gynaecol, Treviso, Italy

[42] Fdn IRCCS Ca Granda Osped Maggiore Policlin, Gynaecol Unit, Milan, Italy

[43] Univ Sassari, Dept Med Surg & Expt Sci, Gynecol & Obstetr Unit, Sassari, Italy

[44] Univ Politecn Marche, Gynecol Sect, Dept Odontostomatol & Specialized Clin Sci, Ancona, Italy

[45] Santa Chiara Hosp, Gynecol Oncol Unit, Trento, Italy

[46] Univ Florence, Careggi Univ Hosp, Dept Biomed Expt & Clin Sci Mario Serio, Gynecol Unit, Florence, Italy

[47] IRCCS Burlo Garofolo, Inst Maternal & Child Hlth, Dept Obstet & Gynaecol, Trieste, Italy

[48] Univ Trieste, Dept Med Surg & Hlth Sci, Trieste, Italy

[49] Madonna Grazie Hosp ASM, Dept Obstet & Gynaecol, Matera, Italy

[50] Osped Valduce, Gynecol Unit, Como, Italy

来源：

JOURNAL OF GYNECOLOGIC ONCOLOGY | 2022年 / 33卷 / 01期

关键词：

Endometrial Cancer; COVID-19; Uterine cancer; SARS-CoV-2; LYMPHADENECTOMY;

D O I：

10.3802/jgo.2022.33.e10

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Objective: Coronavirus disease 2019 (COVID-19) outbreak has correlated with the disruption of screening activities and diagnostic assessments. Endometrial cancer (EC) is one of the most common gynecological malignancies and it is often detected at an early stage, because it frequently produces symptoms. Here, we aim to investigate the impact of COVID-19 outbreak on patterns of presentation and treatment of EC patients. Methods: This is a retrospective study involving 54 centers in Italy. We evaluated patterns of presentation and treatment of EC patients before (period 1: March 1, 2019 to February 29, 2020) and during (period 2: April 1, 2020 to March 31, 2021) the COVID-19 outbreak. Results: Medical records of 5,164 EC patients have been retrieved: 2,718 and 2,446 women treated in period 1 and period 2, respectively. Surgery was the mainstay of treatment in both periods (p=0.356). Nodal assessment was omitted in 689 (27.3%) and 484 (21.2%) patients treated in period 1 and 2, respectively (p<0.001). While, the prevalence of patients undergoing sentinel node mapping (with or without backup lymphadenectomy) has increased during the COVID-19 pandemic (46.7% in period 1 vs. 52.8% in period 2; p<0.001). Overall, 1,280 (50.4%) and 1,021 (44.7%) patients had no adjuvant therapy in period 1 and 2, respectively (p<0.001). Adjuvant therapy use has increased during COVID-19 pandemic (p<0.001). Conclusion: Our data suggest that the COVID-19 pandemic had a significant impact on the characteristics and patterns of care of EC patients. These findings highlight the need to implement healthcare services during the pandemic.

引用

页数：10

共 50 条

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