Antiviral Agents Added to Corticosteroids for Early Treatment of Adults With Acute Idiopathic Facial Nerve Paralysis (Bell Palsy)

被引：15

作者：

Sullivan, Frank ^{[1
,2
,3
,4
]}

Daly, Fergus ^{[5
]}

Gagyor, Ildiko ^{[6
]}

机构：

[1] North York Gen Hosp, Toronto, ON, Canada

[2] Univ Toronto, Dept Family & Community Med, 500 Univ Ave, Toronto, ON M5G 1V7, Canada

[3] Univ Toronto, Dalla Lana Sch Publ Hlth, Toronto, ON, Canada

[4] Inst Clin Evaluat Sci, Toronto, ON, Canada

[5] Frontier Sci Ltd, Grampian View, Scotland

[6] Goettingen Univ Med Ctr, Dept Gen Practice, Gottingen, Germany

来源：

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION | 2016年 / 316卷 / 08期

关键词：

D O I：

10.1001/jama.2016.10160

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

CLINICAL QUESTION Compared with oral corticosteroids alone, are oral antiviral drugs associated with improved outcomes when combined with oral corticosteroids in patients presenting within 72 hours of the onset of Bell palsy? BOTTOM LINE Compared with oral corticosteroids alone, the addition of acyclovir, valacyclovir, or famcyclovir to oral corticosteroids for treatment of Bell palsy was associated with a higher proportion of people who recovered at 3- to 12- month follow-up. The quality of evidence is limited by heterogeneity, imprecision of the result estimates, and risk of bias.

引用

页码：874 / 875

页数：2

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