Differential Pulse Anodic Voltammetric Determination of Tiapride Hydrochloride in Pharmaceutical Preparation and Human Urine Using Carbon Paste Electrodes

被引：5

作者：

Zayed, S. I. M. ^{[1
]}

机构：

[1] Beni Suef Univ, Fac Ind Educ, Bani Suwayf, Egypt

来源：

ANALYTICAL SCIENCES | 2011年 / 27卷 / 05期

关键词：

BENZAMIDES; SPECTROMETRY; EXTRACTION; SERUM;

D O I：

10.2116/analsci.27.535

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

The anodic voltammetric behavior of tiapride hydrochloride (TiapCl) was studied at carbon paste electrodes in 0.04 M Britton-Robinson buffer pH 7.0 using cyclic and differential pulse voltammetric techniques. The oxidation of TiapCl is an irreversible diffusion-controlled process. A differential pulse anodic voltammetric procedure has been developed for determination of the drug over the concentration range 0.36 - 19.35 mu g/ml with detection and quantification limits of 0.12 and 0.40 mu g/ml, respectively. The proposed method was successfully applied for the determination of the drug in commercial tablets and in spiked human urine samples.

引用

页码：535 / 539

页数：5

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[1] Differential Pulse Anodic Voltammetric Determination of Tiapride Hydrochloride in Pharmaceutical Preparation and Human Urine Using Carbon Paste Electrodes
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