ACAT2 as a novel therapeutic target to treat fatty liver disease

被引:5
|
作者
Romeo, Stefano [1 ,2 ,3 ]
机构
[1] Univ Gothenburg, Sahlgrenska Acad, Wallenberg Lab, Dept Mol & Clin Med,Inst Med, Bruna Straket 16, S-41345 Gothenburg, Vastra Gotaland, Sweden
[2] Sahlgrens Univ Hosp, Dept Cardiol, Gothenburg, Sweden
[3] Magna Graecia Univ Catanzaro, Dept Med & Surg Sci, Clin Nutr Unit, Catanzaro, Italy
关键词
NASH; Fatty liver; Soat2; MAFLD; NAFLD;
D O I
10.1111/joim.13460
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:175 / 176
页数:2
相关论文
共 50 条
  • [1] ACAT2 may be a novel predictive biomarker and therapeutic target in lung adenocarcinoma
    Wang, Zhongchao
    Cao, Zhugen
    Dai, Zhaoxia
    CANCER REPORTS, 2024, 7 (02)
  • [2] ACAT2 is a target for treatment of coronary heart disease associated with hypercholesterolemia
    Rudel, LL
    Lee, RG
    Parini, P
    ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2005, 25 (06) : 1112 - 1118
  • [3] Control of ACAT2 liver expression by HNF1
    Pramfalk, C
    Davis, MA
    Eriksson, M
    Rudel, LL
    Parini, P
    JOURNAL OF LIPID RESEARCH, 2005, 46 (09) : 1868 - 1876
  • [4] Gut microbiota: novel therapeutic target for nonalcoholic fatty liver disease
    Suk, Ki Tae
    Kim, Dong Joon
    EXPERT REVIEW OF GASTROENTEROLOGY & HEPATOLOGY, 2019, 13 (03) : 193 - 204
  • [5] The Role of Leaky Gut in Nonalcoholic Fatty Liver Disease: A Novel Therapeutic Target
    Kessoku, Takaomi
    Kobayashi, Takashi
    Tanaka, Kosuke
    Yamamoto, Atsushi
    Takahashi, Kota
    Iwaki, Michihiro
    Ozaki, Anna
    Kasai, Yuki
    Nogami, Asako
    Honda, Yasushi
    Ogawa, Yuji
    Kato, Shingo
    Imajo, Kento
    Higurashi, Takuma
    Hosono, Kunihiro
    Yoneda, Masato
    Usuda, Haruki
    Wada, Koichiro
    Saito, Satoru
    Nakajima, Atsushi
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, 22 (15)
  • [6] ACAT2 Is a Novel Negative Regulator of Pig Intramuscular Preadipocytes Differentiation
    Tian, Ye
    Zhao, Yuelei
    Yu, Wensai
    Melak, Sherif
    Niu, Yingfang
    Wei, Wei
    Zhang, Lifan
    Chen, Jie
    BIOMOLECULES, 2022, 12 (02)
  • [7] Differential modulation of ACAT1 and ACAT2 mRNA and activity by long chain fatty acids in cultured cells
    Seo, T
    Oelkers, PM
    Giattina, MR
    Worgall, TS
    Sturley, SL
    Deckelbaum, RJ
    CIRCULATION, 1999, 100 (18) : 612 - 612
  • [8] Cholesterol and fatty acids regulate cysteine ubiquitylation of ACAT2 through competitive oxidation
    Yong-Jian Wang
    Yan Bian
    Jie Luo
    Ming Lu
    Ying Xiong
    Shu-Yuan Guo
    Hui-Yong Yin
    Xu Lin
    Qin Li
    Catherine C. Y. Chang
    Ta-Yuan Chang
    Bo-Liang Li
    Bao-Liang Song
    Nature Cell Biology, 2017, 19 : 808 - 819
  • [9] Cholesterol and fatty acids regulate cysteine ubiquitylation of ACAT2 through competitive oxidation
    Wang, Yong-Jian
    Bian, Yan
    Luo, Jie
    Lu, Ming
    Xiong, Ying
    Guo, Shu-Yuan
    Yin, Hui-Yong
    Lin, Xu
    Li, Qin
    Chang, Catherine C. Y.
    Chang, Ta-Yuan
    Li, Bo-Liang
    Song, Bao-Liang
    NATURE CELL BIOLOGY, 2017, 19 (07) : 808 - +
  • [10] KISSPEPTIN RECEPTOR: NEW TARGET TO TREAT NONALCOHOLIC FATTY LIVER DISEASE
    Guzman, Stephania
    Dragan, Magdalena
    Kwon, Hyokjoon
    Bhatt, Vrushank
    Shah, Ankit
    Rustgi, Vinod K.
    Dhillo, Waljit S.
    Bech, Paul R.
    Abbara, Ali
    Izzi-Engbeaya, Chioma
    Wang, He
    Guo, Grace L.
    Guo, Jessie Y.
    Wondisford, Frederic E.
    Babwah, Andy V.
    Bhattacharya, Moshmi
    HEPATOLOGY, 2021, 74 : 1074A - 1075A