The process of urbanization has brought about prosperity in urban civilizations, causing a series of ecological and social problems. Therefore, in recent years, monitoring the process of urban expansion has become a hot spot in the field of geosciences. The 8 main urban agglomerations built-up areas from 1995 to 2015 were extracted by night light images. Based on the expansion speed and intensity index, center of gravity migration model, spatial correlation analysis and grey correlation analysis, the characteristics of the spatial and temporal variation were described. Based on it, a driving force model was established to explore the factors behind its spatial and temporal expansion. The built-up areas of the Yangtze River Delta, the Pearl River Delta, the Beijing-Tianjin-Hebei Region, the Chengdu-Chongqing Economic Circle, Central Plains, the middle reaches of the Yangtze River, central Yunnan, and the Beibu Gulf have been increasing year by year, and reached 7671 km(2), 3926 km(2), 3729 km(2), 3025 km(2), 6649 km(2), 3172 km(2), 500 km(2), 1047 km(2) in 2015, which are 5.0, 6.6, 2.6, 5.1, 3.1, 2.8, 3.5, 3.2 times more than that in 1995 respectively. There is an expansion trend of 'point-block-surface' from the overall perspective. The development of all eight urban agglomerations belongs to the spatial expansion mode under the guidance of agglomeration, the spatial distribution presents positive spatial autocorrelation, and the agglomeration degree manifests fluctuating changes. Socio-economic factors such as non-agricultural population, regional Gross Domestic Product, and total industrial output have a greater impact on the expansion of urban built-up areas, while the number of colleges and universities and the total investment in fixed assets have less impact with less synchronization.