Manganese-catalyzed homogeneous hydrogenation of ketones and conjugate reduction of α,/β-unsaturated carboxylic acid derivatives: A chemoselective, robust, and phosphine-free in situ-protocol

被引：8

作者：

Vielhaber, Thomas ^{[1
]}

Topf, Christoph ^{[1
]}

机构：

[1] Johannes Kepler Univ JKU, Inst Catalysis INCA, A-4040 Linz, Austria

来源：

APPLIED CATALYSIS A-GENERAL | 2021年 / 623卷

关键词：

Homogeneous hydrogenation; Conjugate reduction; Manganese; Picolylamine; Chelates; PINCER; COMPLEXES; ALCOHOLS; METHANOL; METHYLATION; ALDEHYDES; EFFICIENT; LIGANDS; CO2;

D O I：

10.1016/j.apcata.2021.118280

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

We communicate a user-friendly and glove-box-free catalytic protocol for the manganese-catalyzed hydrogenation of ketones and conjugated CCbonds of esters and nitriles. The respective catalyst is readily assembled in situ from the privileged [Mn(CO)(5)Br] precursor and cheap 2-picolylamine. The catalytic transformations were performed in the presence of t-BuOK whereby the corresponding hydrogenation products were obtained in good to excellent yields. The described system offers a brisk and atom-efficient access to both secondary alcohols and saturated esters avoiding the use of oxygen-sensitive and expensive phosphine-based ligands.

引用

页数：10