Nanotechnology: A Potential Weapon to Fight against COVID-19

被引:7
|
作者
Tiwari, Atul K. [1 ]
Mishra, Anupa [2 ,3 ]
Pandey, Govind [4 ]
Gupta, Munesh K. [5 ]
Pandey, Prem C. [1 ]
机构
[1] Indian Inst Technol BHU, Dept Chem, Varanasi 221005, Uttar Pradesh, India
[2] Dr RML Awadh Univ, Dept Microbiol, Ayodhya 224001, Uttar Pradesh, India
[3] Sri Raghukul Mahila Vidya Peeth, Dept Microbiol, Civil Line Gonda 271001, Uttar Pradesh, India
[4] King George Med Univ, Dept Paediat, Lucknow 226003, Uttar Pradesh, India
[5] Banaras Hindu Univ, Inst Med Sci, Dept Microbiol, Varanasi 221005, Uttar Pradesh, India
关键词
antiviral drugs; biosensors; drug delivery; nanoformulations; nanotechnology; vaccines; HERPES-SIMPLEX-VIRUS; FIELD-EFFECT TRANSISTOR; ENHANCED PHOTODYNAMIC THERAPY; SYNDROME-RELATED CORONAVIRUS; MXENES COMPOSITE NANOSHEETS; CELL-PENETRATING PEPTIDES; H1N1; INFLUENZA-VIRUS; INFECTION IN-VITRO; SILVER NANOPARTICLES; GRAPHENE OXIDE;
D O I
10.1002/ppsc.202100159
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
The COVID-19 infections have posed an unprecedented global health emergency, with nearly three million deaths to date, and have caused substantial economic loss globally. Hence, an urgent exploration of effective and safe diagnostic/therapeutic approaches for minimizing the threat of this highly pathogenic coronavirus infection is needed. As an alternative to conventional diagnosis and antiviral agents, nanomaterials have a great potential to cope with the current or even future health emergency situation with a wide range of applications. Fundamentally, nanomaterials are physically and chemically tunable and can be employed for the next generation nanomaterial-based detection of viral antigens and host antibodies in body fluids as antiviral agents, nanovaccine, suppressant of cytokine storm, nanocarrier for efficient delivery of antiviral drugs at infection site or inside the host cells, and can also be a significant tool for better understanding of the gut microbiome and SARS-CoV-2 interaction. The applicability of nanomaterial-based therapeutic options to cope with the current and possible future pandemic is discussed here.
引用
收藏
页数:26
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