High spatial resolution inorganic scintillator detector for high-energy X-ray beam at small field irradiation

被引:24
|
作者
Debnath, Sree Bash Chandra [1 ]
Fauquet, Carole [1 ]
Tallet, Agnes [2 ]
Goncalves, Anthony [3 ]
Lavandier, Sebastien [1 ]
Jandard, Franck [1 ]
Tonneau, Didier [1 ]
Darreon, Julien [2 ]
机构
[1] Aix Marseille Univ, CNRS, CINaM UMR 7325, F-13288 Marseille, France
[2] Inst Paoli Calmettes, F-13009 Marseille, France
[3] Aix Marseille Univ, CNRS, UMR 7258, CRCM,INSERM,UMR 1068, F-13009 Marseille, France
基金
欧盟地平线“2020”;
关键词
inorganic scintillator detector; micro-scintillators; real-time radiation dose; small field irradiation; X-ray detector; EXRADIN W1 SCINTILLATOR; DOSIMETRY; MICRODIAMOND; PERFORMANCE; SYSTEM; PHOTON; SENSOR;
D O I
10.1002/mp.14002
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Purpose Small field dosimetry for radiotherapy is one of the major challenges due to the size of most dosimeters, for example, sufficient spatial resolution, accurate dose distribution and energy dependency of the detector. In this context, the purpose of this research is to develop a small size scintillating detector targeting small field dosimetry and compare its performance with other commercial detectors. Method An inorganic scintillator detector (ISD) of about 200 mu m outer diameter was developed and tested through different small field dosimetric characterizations under high-energy photons (6 and 15 MV) delivered by an Elekta Linear Accelerator (LINAC). Percentage depth dose (PDD) and beam profile measurements were compared using dosimeters from PTW namely, microdiamond and PinPoint three-dimensional (PP3D) detector. A background fiber method has been considered to quantitate and eliminate the minimal Cerenkov effect from the total optical signal magnitude. Measurements were performed inside a water phantom under IAEA Technical Reports Series recommendations (IAEA TRS 381 and TRS 483). Results Small fields ranging from 3 x 3 cm(2), down to 0.5 x 0.5 cm(2) were sequentially measured using the ISD and commercial dosimeters, and a good agreement was obtained among all measurements. The result also shows that, scintillating detector has good repeatability and reproducibility of the output signal with maximum deviation of 0.26% and 0.5% respectively. The Full Width Half Maximum (FWHM) was measured 0.55 cm for the smallest available square size field of 0.5 x 0.5 cm(2), where the discrepancy of 0.05 cm is due to the scattering effects inside the water and convolution effect between field and detector geometries. Percentage depth dose factor dependence variation with water depth exhibits nearly the same behavior for all tested detectors. The ISD allows to perform dose measurements at a very high accuracy from low (50 cGy/min) to high dose rates (800 cGy/min) and was found to be independent of dose rate variation. The detection system also showed an excellent linearity with dose; hence, calibration was easily achieved. Conclusions The developed detector can be used to accurately measure the delivered dose at small fields during the treatment of small volume tumors. The author's measurement shows that despite using a nonwater-equivalent detector, the detector can be a powerful candidate for beam characterization and quality assurance in, for example, radiosurgery, Intensity-Modulated Radiotherapy (IMRT), and brachytherapy. Our detector can provide real-time dose measurement and good spatial resolution with immediate readout, simplicity, flexibility, and robustness.
引用
收藏
页码:1364 / 1371
页数:8
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