Hepatitis C virus infection in children

被引：0
|
作者：
Cuarterolo, Miriam [1 ]
Lopez, Susana [1 ]
Ciocca, Mirta [1 ]
机构：
[1] Hosp Nacl Pediat Prof Dr Juan P Garrahan, Buenos Aires, DF, Argentina
来源：
ARCHIVOS ARGENTINOS DE PEDIATRIA | 2011年 / 109卷 / 03期
关键词：
hepatitis C; children; chronic hepatitis; epidemiology; treatment; SUSTAINED VIROLOGICAL RESPONSE; ALPHA-2B PLUS RIBAVIRIN; TO-INFANT TRANSMISSION; COMBINATION THERAPY; PEGINTERFERON; ADOLESCENTS; HCV; INTERFERON; CLEARANCE; DISEASE;
D O I：
暂无
中图分类号：
R72 [儿科学];
学科分类号：
100202 ;
摘要：
The modes of transmission of hepatitis C virus are parenteral, sexual and maternal-fetal. It affects 3% of the population worldwide. Currently, vertical infection is the main way of virus spreading. Most children are clinically asymptomatic, but progression of liver disease has been described. The positivity of antibodies against hepatitis C virus does not discriminate between active and resolved infection, so determination of serum HCV-RNA is necessary. The combination of peginterferon and ribavirin appears to be the most effective treatment. Future challenges are the development of new drugs and a vaccine.
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页码：245 / 250
页数：6
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