Drugging the undruggable

被引：3
|
作者：
Mayer, JR [1 ]
DiMarchi, RD
机构：
[1] Lilly Corp Ctr, Lilly Res Labs, Indianapolis, IN 46285 USA
[2] Indiana Univ, Dept Chem, Bloomington, IN 47405 USA
来源：
CHEMISTRY & BIOLOGY | 2005年 / 12卷 / 08期
关键词：
D O I：
10.1016/j.chembiol.2005.08.004
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
In this issue of Chemistry & Biology, Li and Lawrence [1] report an iterative synthesis/selection process to identify chemically modified peptide ligands possessing high affinity and selectivity for the SH3 domain of Fyn, a member of the Src kinase family.
引用
收藏
页码：860 / 861
页数：2
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