Micro-optical fiber probe for use in an intravascular Raman endoscope

被引:80
|
作者
Komachi, Y [1 ]
Sato, H
Aizawa, K
Tashiro, H
机构
[1] RIKEN, Probing Technol Lab, Inst Phys & Chem Res, Wako, Saitama 3510198, Japan
[2] Machida Endoscope Co Ltd, Bunkyo Ku, Tokyo 1130021, Japan
[3] Tokyo Med Univ, Dept Physiol, Shinjuku Ku, Tokyo 1608402, Japan
关键词
D O I
10.1364/AO.44.004722
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
We believe that we have developed the narrowest optical-fiber Raman probe ever reported, 600 mu m in total diameter, that can be inserted into coronary arteries. The selection of suitable optical fibers, filters, and a processing method is discussed. Custom-made filters attached to the front end of a probe eliminate the background Raman signals of the optical fiber itself. The experimental evaluation of various optical fibers is carried out for the selection of suitable fibers. Measurement of the Raman spectra of an atherosclerotic lesion of a rabbit artery in vitro demonstrates the excellent performance of the micro-Raman probe. (c) 2005 Optical Society of America.
引用
收藏
页码:4722 / 4732
页数:11
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