Tumor mutational burden and immune signatures interplay in renal cell carcinoma

被引:16
|
作者
Yakirevich, Evgeny
Patel, Nimesh R.
机构
[1] Brown Univ, Rhode Isl Hosp, Dept Pathol, Providence, RI 02903 USA
[2] Brown Univ, Alpert Med Sch, Providence, RI 02912 USA
关键词
CANCER; LYMPHOCYTES; NEOANTIGENS; ACTIVATION;
D O I
10.21037/atm.2020.02.81
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页数:5
相关论文
共 50 条
  • [1] Tumor mutational burden and immune infiltrates in renal cell carcinoma and matched brain metastases
    Steindl, A.
    Alpar, D.
    Heller, G.
    Mair, M. J.
    Gatterbauer, B.
    Dieckmann, K.
    Widhalm, G.
    Hainfellner, J. A.
    Schmidinger, M.
    Bock, C.
    Muellauer, L.
    Preusser, M.
    Berghoff, A. S.
    [J]. ESMO OPEN, 2021, 6 (02)
  • [2] MUTATIONAL AND PROGNOSTIC ASSOCIATIONS OF IMMUNE CELL SIGNATURES IN CLEAR CELL RENAL CELL CARCINOMA
    Winer, Andrew
    Senbabaoglu, Yasin
    Kaffenberger, Samuel
    Coleman, Jonathan
    Russo, Paul
    Sander, Chris
    Hsieh, James
    Hakimi, Ari
    [J]. JOURNAL OF UROLOGY, 2015, 193 (04): : E556 - E557
  • [3] Actionable mutations and mutational burden in renal cell carcinoma
    Mockus, Susan M.
    Patterson, Sara E.
    Pettus, Jason R.
    Tsongalis, Gregory J.
    [J]. CANCER RESEARCH, 2016, 76
  • [4] The clinical significance, immune infiltration, and tumor mutational burden of angiogenesis-associated lncRNAs in kidney renal clear cell carcinoma
    Zhang, Wei
    Liu, Zhiming
    Wang, Jinpeng
    Geng, Bo
    Hou, Wenbin
    Zhao, Enyang
    Li, Xuedong
    [J]. FRONTIERS IN IMMUNOLOGY, 2022, 13
  • [5] Tumour mutational burden and immune infiltrates in primary renal cell carcinoma and matched brain metastases
    Steindl, A.
    Bergen, E. S.
    Alpar, D.
    Gatterbauer, B.
    Dieckmann, K.
    Widhalm, G.
    Hainfellner, J. A.
    Schmidinger, M.
    Bock, C.
    Muellauer, L.
    Preusser, M.
    Berghoff, A. S.
    [J]. ANNALS OF ONCOLOGY, 2019, 30
  • [6] Prognostic Value of Tumor Mutational Burden Related to Immune Infiltration in Cervical Squamous Cell Carcinoma
    Wen, Fang
    Ruan, Shuai
    Huang, Wenjie
    Chen, Xiaoxue
    Wang, Yulan
    Gu, Suping
    Liu, Jiatong
    Liu, Shenlin
    Shu, Peng
    [J]. FRONTIERS IN MEDICINE, 2021, 8
  • [7] Relationship of tumor mutational burden (TMB) to immunotherapy response in metastatic renal cell carcinoma (mRCC).
    Maia, Manuel C.
    Almeida, Lorena
    Bergerot, Paulo Gustavo
    Dizman, Nazli
    Pal, Sumanta K.
    [J]. JOURNAL OF CLINICAL ONCOLOGY, 2018, 36 (06)
  • [8] Tumor Mutational Burden Predicts Survival in Merkel Cell Carcinoma
    Smith, J. D.
    Bhangale, A.
    Gu, W.
    Gensterblum-Miller, E.
    Brummel, C.
    Spector, M. E.
    Mills, R.
    Brenner, C.
    [J]. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2024, 118 (05): : E74 - E74
  • [9] Tumor Mutational Load and Immune Parameters across Metastatic Renal Cell Carcinoma Risk Groups
    de Velasco, Guillermo
    Miao, Diana
    Voss, Martin H.
    Hakimi, A. Ari
    Hsieh, James J.
    Tannir, Nizar M.
    Tamboli, Pheroze
    Appleman, Leonard J.
    Rathmell, W. Kimryn
    Van Allen, Eliezer M.
    Choueiri, Toni K.
    [J]. CANCER IMMUNOLOGY RESEARCH, 2016, 4 (10) : 820 - 822
  • [10] Determinants of high tumor mutational burden (TMB) and mutational signatures in breast cancer
    Barroso-Sousa, Romualdo
    Jain, Esha
    Kim, Dewey
    Partridge, Ann H.
    Cohen, Ofir
    Wagle, Nikhil
    [J]. JOURNAL OF CLINICAL ONCOLOGY, 2018, 36 (15)