Hepatic oxidative stress activates the Gadd45b gene via degradation of the transcriptional repressor STAT3

被引:0
|
作者
Kim, Jung-Hwan [1 ]
Qu, Aijuan [1 ]
Reddy, Janardan K. [2 ]
Gao, Bin [3 ]
Gonzalez, Frank J. [1 ]
机构
[1] NCI, Bethesda, MD 20892 USA
[2] Northwestern Univ, Feiberg Sch Med, Evanston, IL 60208 USA
[3] NIAAA, Lab Liver Dis, Rockville, MD 20852 USA
关键词
D O I
10.1158/1538-7445.AM2014-492
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
492
引用
收藏
页数:2
相关论文
共 50 条
  • [1] Hepatic Oxidative Stress Activates the Gadd45b Gene by Way of Degradation of the Transcriptional Repressor STAT3
    Kim, Jung-Hwan
    Qu, Aijuan
    Reddy, Janardan K.
    Gao, Bin
    Gonzalez, Frank J.
    [J]. HEPATOLOGY, 2014, 59 (02) : 695 - 704
  • [3] Does Monosodium Glutamate Induce Genotoxic Stress Through Altering Gadd45b Gene Expression?
    Hamdy, Germine M.
    Saleh, Eman M.
    Seoudi, Dina M.
    [J]. RESEARCH JOURNAL OF PHARMACEUTICAL BIOLOGICAL AND CHEMICAL SCIENCES, 2018, 9 (03): : 1058 - 1070
  • [4] Loss of Stress Sensor GADD45a and GADD45b Accelerates BCR-ABL-Driven Leukemogenesis Via Distinct Signaling and Cellular Pathways
    Sha, Xiaojin
    Hoffman, Barbara
    [J]. BLOOD, 2010, 116 (21) : 521 - 522
  • [5] Gadd45a Suppresses Tumor Angiogenesis via Inhibition of the mTOR/STAT3 Protein Pathway
    Yang, Fang
    Zhang, Weimin
    Li, Dan
    Zhan, Qimin
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2013, 288 (09) : 6552 - 6560
  • [6] Large hepatitis delta antigen activates STAT-3 and NF-?B via oxidative stress
    Williams, V.
    Brichler, S.
    Khan, E.
    Chami, M.
    Deny, P.
    Kremsdorf, D.
    Gordien, E.
    [J]. JOURNAL OF VIRAL HEPATITIS, 2012, 19 (10) : 744 - 753
  • [7] Transcription factor E2F3 up-regulates the expression of Gadd45b gene in the mouse liver
    Kim, Jung-Hwan
    Gonzalez, Frank J.
    [J]. CANCER RESEARCH, 2016, 76
  • [8] Transcriptional stimulation of the surfactant protein B gene by STAT3 in respiratory epithelial cells
    Yan, C
    Naltner, A
    Martin, M
    Naltner, M
    Fangman, JM
    Gurel, O
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2002, 277 (13) : 10967 - 10972
  • [9] Fluorescent labeling of CRISPR/Cas9 RNP for gene knockout in HSPCs and iPSCs reveals an essential role for GADD45b in stress response
    Nasri, Masoud
    Mir, Perihan
    Dannenmann, Benjamin
    Amend, Diana
    Skroblyn, Tessa
    Xu, Yun
    Schulze-Osthoff, Klaus
    Klimiankou, Maksim
    Welte, Karl
    Skokowa, Julia
    [J]. BLOOD ADVANCES, 2019, 3 (01) : 63 - 71
  • [10] Proteolysis-inducing factor regulates hepatic gene expression via the transcription factors NF-κB and STAT3
    Watchorn, TM
    Waddell, I
    Dowidar, N
    Ross, JA
    [J]. FASEB JOURNAL, 2001, 15 (03): : 562 - 564