Low-grade non-Hodgkin's lymphoma in a patient with systemic lupus erythematosus

被引:7
|
作者
Robak, T [1 ]
Robak, E [1 ]
Bartkowiak, J [1 ]
Blonski, JZ [1 ]
Niewiadomska, H [1 ]
Wawrzyniak, E [1 ]
机构
[1] Med Univ Lodz, Dept Hematol, Lodz, Poland
关键词
systemic lupus erythematosus; lymphoma; autoimmune disease; immunophenotype; gamma delta T cells; CD5+Blymphocytes;
D O I
10.3109/10428190109060357
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Coexistence of systemic lupus erythematosus (SLE) with low-grade non-Hodgkin's lymphoma (LGNHL) has been described occasionally in the literature with the potential pathogenetic role of monoclonal B CD5+/CD19+ cells. We report a case of LGNHL which developed 18 months after diagnosis of SLE. The monoclonal population of lymphocytes ia the peripheral blood and bone marrow was CD5/CD19 negative but CD19/CD22 positive. The SLE responded well to treatment with prednisone and the course of the LGNHL was stable and cytotoxic treatment was not required.
引用
收藏
页码:659 / +
页数:13
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