Antibody-functionalized SERS tags with improved sensitivity

被引：32
|
作者：
Guarrotxena, Nekane [1 ,2 ]
Bazan, Guillermo C. [2 ]
机构：
[1] CSIC, Inst Ciencia & Tecnol Polimeros, E-28006 Madrid, Spain
[2] Univ Calif Santa Barbara, Dept Chem & Biochem & Mat, Inst Polymers & Organ Solids, Santa Barbara, CA 93106 USA
来源：
CHEMICAL COMMUNICATIONS | 2011年 / 47卷 / 31期
基金：
美国国家科学基金会;
关键词：
ENHANCED RAMAN-SPECTROSCOPY; GOLD NANOPARTICLES; ULTRASENSITIVE DETECTION; PROTEIN RECOGNITION; SINGLE-MOLECULE; DNA; NANOSCALE;
D O I：
10.1039/c1cc12659h
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Protein detection at the femtomolar level can be achieved by using metallic nanoparticle assemblies that function as surface enhanced Raman spectroscopy reporters and that contain suitable surface-bound recognition elements. Proper control of the interaction between nanoparticles within the assemblies is critical for achieving this performance.
引用
收藏
页码：8784 / 8786
页数：3
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