As the number of COVID-19 cases rose in the US and around the world in early 2020, conservative elites in the US racialized the pandemic, referring to the coronavirus as the "Chinese flu" or the "Wuhan virus." Existing research suggests that this linking of the viral pandemic to a social group will "activate" anti-Asian attitudes in the mass public, helping bring those attitudes to bear on behaviors and attitudes related to COVID-19. Despite anecdotal evidence of a spike in discriminatory behavior targeted at Asians across western countries, little empirical evidence for this "othering" hypothesis exists. Using a large survey (n = 4311) benchmarked to national demographics, we analyze the relationship between attitudes toward Asian Americans, xenophobia, concern about contracting the coronavirus, and a variety of behavioral outcomes and policy attitudes. We find evidence that anti-Asian attitudes are associated with concern about the virus but also with xenophobic behaviors and policy preferences. These relationships are unique to Asian American attitudes, are not related to attitudes toward other outgroups, and do not hold for a variety of placebo outcomes. Together our findings suggest that anti-Asian attitudes were activated and were associated with a variety of COVID-19 attitudes and behaviors in the early stages of the pandemic.