Knowledge-based protein structure prediction.

被引：0

作者：

Zhao, SR ^{[1
]}

Yun, T ^{[1
]}

Chen, KX ^{[1
]}

机构：

[1] CHINESE ACAD SCI,SHANGHAI INST MAT MED,SHANGHAI 200031,PEOPLES R CHINA

来源：

PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS | 1996年 / 23卷 / 05期

关键词：

three-dimensional structure prediction; homologous protein modeling; inverse protein folding; sequence structure alignment;

D O I：

暂无

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The methods and progress of knowledge-based protein three-dimensional structure prediction are mainly introduced. To date, the methods of knowledge-based structure prediction can be grouped into two categories. One is homologous protein modeling, which is relative mature and can give reliable results, but it is restricted to modeling of the target sequence that shares a high sequence identity with the homologous proteins. The other method, inverse protein folding, can be employed to predict the structure of protein with limited sequence homology, which mainly includes 3D Profile and potential-based functions, and gives the topology of the target protein.

引用

页码：422 / 426

页数：5

共 22 条

[1] RECOGNITION OF DISTANTLY RELATED PROTEINS THROUGH ENERGY CALCULATIONS
ABAGYAN, R
FRISHMAN, D
ARGOS, P
[J]. PROTEINS-STRUCTURE FUNCTION AND GENETICS, 1994, 19 (02): : 132 - 140
[2] A METHOD TO IDENTIFY PROTEIN SEQUENCES THAT FOLD INTO A KNOWN 3-DIMENSIONAL STRUCTURE
BOWIE, JU
LUTHY, R
EISENBERG, D
[J]. SCIENCE, 1991, 253 (5016) : 164 - 170
[3] AN EMPIRICAL ENERGY FUNCTION FOR THREADING PROTEIN-SEQUENCE THROUGH THE FOLDING MOTIF
BRYANT, SH
LAWRENCE, CE
[J]. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 1993, 16 (01) : 92 - 112
[4] EINSENHABER F, 1995, CRIT REV BIOCHEM MOL, V30, P1
[5] COMPARISON OF SYSTEMATIC SEARCH AND DATABASE METHODS FOR CONSTRUCTING SEGMENTS OF PROTEIN-STRUCTURE
FIDELIS, K
STERN, PS
BACON, D
MOULT, J
[J]. PROTEIN ENGINEERING, 1994, 7 (08): : 953 - 960
[6] PREDICTING THE STRUCTURE OF THE FLAVODOXIN FROM ESCHERICHIA-COLI BY HOMOLOGY MODELING, DISTANCE GEOMETRY AND MOLECULAR-DYNAMICS
HAVEL, TF
[J]. MOLECULAR SIMULATION, 1993, 10 (2-6) : 175 - 210
[7] SIDE-CHAIN PREDICTION BY NEURAL NETWORKS AND SIMULATED ANNEALING OPTIMIZATION
HWANG, JK
LIAO, WF
[J]. PROTEIN ENGINEERING, 1995, 8 (04): : 363 - 370
[8] KNOWLEDGE-BASED PROTEIN MODELING
JOHNSON, MS
SRINIVASAN, N
SOWDHAMINI, R
BLUNDELL, TL
[J]. CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY, 1994, 29 (01) : 1 - 68
[9] PROTEIN MODELING USING A CHIMERA REFERENCE PROTEIN-DERIVED FROM EXONS
KAJIHARA, A
KOMOOKA, H
KAMIYA, K
UMEYAMA, H
[J]. PROTEIN ENGINEERING, 1993, 6 (06): : 615 - 620
[10] FACTORS INFLUENCING THE ABILITY OF KNOWLEDGE-BASED POTENTIALS TO IDENTIFY NATIVE SEQUENCE-STRUCTURE MATCHES
KOCHER, JPA
ROOMAN, MJ
WODAK, SJ
[J]. JOURNAL OF MOLECULAR BIOLOGY, 1994, 235 (05) : 1598 - 1613

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