Surgical management of glioneuronal tumors with drug-resistant epilepsy

被引：16
|
作者：
Zaghloul, Kareem A. [2 ]
Schramm, Johannes [1 ]
机构：
[1] Univ Bonn, Dept Neurosurg, D-53105 Bonn, Germany
[2] NINDS, Surg Neurol Branch, NIH, Bethesda, MD 20892 USA
来源：
ACTA NEUROCHIRURGICA | 2011年 / 153卷 / 08期
关键词：
Glioneuronal tumors; Ganglioglioma; DNT; Epilepsy; TEMPORAL-LOBE EPILEPSY; DYSEMBRYOPLASTIC NEUROEPITHELIAL TUMOR; LONG-TERM SEIZURE; INTRACTABLE EPILEPSY; BRAIN-TUMORS; INTRAOPERATIVE ELECTROCORTICOGRAPHY; EPILEPTOGENIC GANGLIOGLIOMAS; FUNCTIONAL CONNECTIVITY; PROGNOSTIC-FACTORS; ADULT PATIENTS;
D O I：
10.1007/s00701-011-1050-1
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
In this review, we discuss the options for the surgical management of glioneuronal tumors (GNTs) associated with drug-resistant epilepsy, with an emphasis on the surgical issues involved in addressing the epileptogenic nature of these lesions. We briefly summarize the pathological hallmarks of these lesions in order to outline how these tumors contribute to seizure activity. Understanding the pathophysiology of these lesions is important in discussing the advantages and disadvantages of different surgical strategies. There have been a number of studies that have investigated the utility of different surgical approaches in improving seizure outcome, and we highlight some of these studies in order to shed light on surgical issues related to these tumors.
引用
收藏
页码：1551 / 1559
页数：9
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