Coupling the lattice-Boltzmann and spectrin-link methods for the direct numerical simulation of cellular blood flow

被引:76
|
作者
Reasor, Daniel A., Jr. [1 ]
Clausen, Jonathan R. [1 ]
Aidun, Cyrus K. [1 ]
机构
[1] Georgia Inst Technol, George W Woodruff Sch Mech Engn, Atlanta, GA 30332 USA
基金
美国国家科学基金会;
关键词
lattice-Boltzmann; spectrin-link modeling; red blood cells; multiphase flow; PARTICULATE SUSPENSIONS; OPTICAL TWEEZERS; ERYTHROCYTE; MECHANICS; EQUATION; MODEL; FLUID; DNA;
D O I
10.1002/fld.2534
中图分类号
TP39 [计算机的应用];
学科分类号
081203 ; 0835 ;
摘要
The implementation of a spectrin-link (SL) red blood cell (RBC) membrane method coupled with a lattice-Boltzmann (LB) fluid solver is discussed. Details of the methodology are included along with subtleties associated with its integration into a massively parallel hybrid LB finite element (FE) suspension flow solver. A comparison of the computational performance of the coupled LB-SL method with that of the previously implemented LB-FE is given for an isolated RBC and for a dense suspension in Hagen-Poiseuille flow. Validating results for RBCs isolated in shear and parachuting in microvessel flow are also presented. Copyright (C) 2011 John Wiley & Sons, Ltd.
引用
收藏
页码:767 / 781
页数:15
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