Cognitive and neurodevelopmental effects of antiepileptic drugs

被引:31
|
作者
Bromley, Rebecca L. [2 ]
Leeman, Beth A. [3 ]
Baker, Gus A. [1 ]
Meador, Kimford J. [3 ]
机构
[1] Univ Liverpool, Clin Sci Ctr Res & Educ, Dept Mol & Clin Pharmacol, Liverpool L9 7LJ, Merseyside, England
[2] Univ Manchester, Div Clin Psychol, Sch Psychol Sci, Manchester, Lancs, England
[3] Emory Univ, Dept Neurol, Atlanta, GA 30322 USA
关键词
Epilepsy; Cognitive dysfunction; Pregnancy; Neurodevelopment; Antiepileptic drugs; QUALITY-OF-LIFE; TEMPORAL-LOBE EPILEPSY; IN-UTERO EXPOSURE; FOCAL INTERICTAL SPIKES; WORKING-MEMORY LOAD; GAMMA-BAND; EPILEPTIFORM ACTIVITY; PRENATAL EXPOSURE; CHILDREN BORN; REACTION-TIME;
D O I
10.1016/j.yebeh.2011.04.009
中图分类号
B84 [心理学]; C [社会科学总论]; Q98 [人类学];
学科分类号
03 ; 0303 ; 030303 ; 04 ; 0402 ;
摘要
This article primarily represents the contributions of two young investigators to the understanding of the neuropsychological consequences of epilepsy and its treatment. The authors have reviewed two key areas of importance: the complex relationship between cognitive dysfunction and epilepsy and the risks of cognitive dysfunction in children as a consequence of in utero exposure to antiepileptic drug treatment. The work of two young investigators is presented and future research needs are outlined. (C) 2011 Published by Elsevier Inc.
引用
收藏
页码:9 / 16
页数:8
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