Teaching NeuroImages: Colchicine-induced vacuolar myopathy

被引：0
|
作者：
Sista, Sri Raghav [1 ]
Nyce, Maxwell Q. [1 ]
Bach, Sarah E. [1 ]
Blume, Gregory M. [1 ]
机构：
[1] Univ Illinois, Coll Med, Dept Neurol, Peoria, IL 61656 USA
来源：
NEUROLOGY | 2019年 / 93卷 / 24期
关键词：
D O I：
10.1212/WNL.0000000000008636
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
An 86-year-old man presented with 1 year of insidiously progressive weakness that started around 2 weeks after colchicine initiation for gout. Examination noted proximal more than distal weakness with diffuse hyporeflexia. Creatine kinase was 3,172 U/mL and electrodiagnostic study was consistent with a myopathic process. Muscle biopsy (figure) showed necrotizing myopathy with vacuoles, as well as mild chronic denervation/reinnervation. Weakness improved after cessation of colchicine. © 2019 American Academy of Neurology.
引用
收藏
页码：E2306 / E2307
页数：2
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