Parotid metastases from thyroid carcinomas

Parotid metastases (PMs) that originate from thyroid carcinomas (TCs) are extremely rare, and many questions about their diagnosis and management remain unanswered. Of the 15,780 patients with TC that we had prospectively recorded in our institutional databases between 1996 and 2015, we retrospectively retrieved only three patients (0.019%) with PM. Patient characteristics, histological findings on initial thyroidectomy and parotidectomy specimens, treatments, and times of recurrence and death were reviewed. In addition, we searched PubMed, Embase, and ISI Web of Science databases (1996-2015) for articles published in the English language using the key words "parotid" and "thyroid", and reviewed almost all reports that described PM that were derived from TC. These rare cases of thyroid carcinoma presenting as metastasis in the parotid gland highlight the importance of maintaining close communication between clinicians, radiologists, and histopathologists to ensure that such rare cases are not missed.