Overexpression of Nonaggregatable α-Synuclein Protects Against Human Wild-Type α-Synuclein-Mediated Toxicity

被引：0
|
作者：
Kanaan, N. M. [1 ]
Kuhn, N. C. [1 ]
Sortwell, C. S. [1 ]
Jiang, C. [2 ]
Manfredsson, F. P. [1 ]
机构：
[1] Michigan State Univ, Coll Human Med, Dept Translat Sci & Mol Med, Grand Rapids, MI USA
[2] Univ Texas Houston, Hlth Sci Ctr, Ctr Prote & Syst Biol, Houston, TX USA
来源：
CELL TRANSPLANTATION | 2012年 / 21卷 / 04期
关键词：
D O I：
暂无
中图分类号：
Q813 [细胞工程];
学科分类号：
摘要：
引用
下载
收藏
页码：783 / 783
页数：1
相关论文
共 50 条
  • [1] Fractalkine Overexpression Suppresses α-Synuclein-Mediated Neurodegeneration
    Nash, J. R.
    Moran, P.
    Finneran, D. J.
    Hudson, C.
    Robinson, J.
    Morgan, D.
    Bickford, P. C.
    CELL TRANSPLANTATION, 2015, 24 (04) : 766 - 767
  • [2] Overexpression of Non-Aggregatable Alpha-Synuclein Protects Against Human Wildtype Alpha-Synuclein Mediated Toxicity
    Kanaan, Nicholas M.
    Kuhn, Nathan C.
    Sortwell, Caryl S.
    Jiang, Chuantao
    Manfredsson, Fredric P.
    MOLECULAR THERAPY, 2012, 20 : S32 - S32
  • [3] Human wild-type α-synuclein impairs neurogenesis
    Winner, B
    Lie, DCH
    Rockenstein, E
    Aigner, R
    Aigner, L
    Masliah, E
    Kuhn, HG
    Winkler, J
    JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY, 2004, 63 (11): : 1155 - 1166
  • [4] Overexpression of wild-type and mutant α-synuclein in a neuroblastoma cell line
    Korlipara, LP
    Messmer, K
    Cooper, JM
    Schapira, AHV
    MOVEMENT DISORDERS, 2002, 17 : S61 - S61
  • [5] α-Synuclein Overexpression in the Aged Brain: Is the Aging Nigrostriatal System More Susceptible to α-Synuclein-Mediated Neurodegeneration?
    Gombash, S. E.
    Manfredsson, F. P.
    Kemp, C. J.
    Wohlgenant, S. L.
    Fischer, D. L.
    Daley, B. F.
    Collier, T. J.
    Lipton, J. W.
    Cole-Strauss, A.
    Mandel, R. J.
    Fleming, S. M.
    Sortwell, C. E.
    CELL TRANSPLANTATION, 2012, 21 (04) : 779 - 780
  • [6] Aggregates Assembled From Overexpression of Wild-Type α-Synuclein are not Toxic to Human Neuronal Cells
    Ko, Li-wen
    Ko, Hwai-hwa C.
    Lin, Wen-Lang
    Kulathingal, Jayanranyan G.
    Yen, Shu-Hui C.
    JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY, 2008, 67 (11): : 1084 - 1096
  • [7] Trehalose inhibits wild-type α-synuclein fibrillation and overexpression and protects against the protein neurotoxicity in transduced PC12 cells
    Jiang, Teng
    Yu, Wen-Bo
    Yao, Ting
    Zhi, Xiu-Ling
    Pan, Luan-Feng
    Wang, Jian
    Zhou, Ping
    RSC ADVANCES, 2013, 3 (24): : 9500 - 9508
  • [8] Effect of the overexpression of wild-type or mutant α-synuclein on cell susceptibility to insult
    Lee, M
    Hyun, DH
    Halliwell, B
    Jenner, P
    JOURNAL OF NEUROCHEMISTRY, 2001, 76 (04) : 998 - 1009
  • [9] Locomotor differences in mice expressing wild-type human α-synuclein
    Giraldo, Genesys
    Brooks, Mieu
    Giasson, Benoit I.
    Janus, Christopher
    NEUROBIOLOGY OF AGING, 2018, 65 : 140 - 148
  • [10] Sumoylation Protects Against β-Synuclein Toxicity in Yeast
    Popova, Blagovesta
    Kleinknecht, Alexandra
    Arendarski, Patricia
    Mischke, Jasmin
    Wang, Dan
    Braus, Gerhard H.
    FRONTIERS IN MOLECULAR NEUROSCIENCE, 2018, 11
12345