Bariatric surgery for the treatment of type 2 diabetes mellitus

被引：3
|
作者：
Benaiges Boix, David [1 ,2 ]
Goday Arno, Albert [1 ,2 ]
Pedro-Botet, Juan [2 ,3 ]
机构：
[1] Hosp del Mar, Serv Endocrinol & Nutr, Barcelona, Spain
[2] Univ Autonoma Barcelona, Dept Med, E-08193 Barcelona, Spain
[3] Hosp del Mar, Unitat Lipids & Risc Vasc, Barcelona, Spain
来源：
MEDICINA CLINICA | 2012年 / 138卷 / 09期
关键词：
Type 2 diabetes mellitus; Bariatric surgery; Obesity; Y GASTRIC BYPASS; GLUCAGON-LIKE PEPTIDE-1; LAPAROSCOPIC SLEEVE GASTRECTOMY; BETA-CELL FUNCTION; WEIGHT-LOSS; GLUCOSE-METABOLISM; INSULIN-RESISTANCE; GENE-EXPRESSION; OBESE-PATIENTS; SECRETION;
D O I：
10.1016/j.medcli.2011.04.009
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Weight loss can improve metabolic control in patients with type 2 diabetes mellitus but the results of conventional therapy in this respect have been discouraging. Besides achieving significant and sustained weight loss, bariatric surgery can improve or resolve type 2 diabetes mellitus in the majority of patients. Anatomical modifications and changes in the secretion of intestinal hormones can explain the superiority of malabsorptive techniques. Currently, bariatric surgery offers a therapeutic alternative for type 2 diabetes patients with severe obesity and poor metabolic control under conventional therapy. Ongoing research will provide insights regarding the effect of intestinal hormones, new surgery techniques and the possible benefits of bariatric surgery in non-obese patients. (C) 2011 Elsevier Espana, S.L. All rights reserved.
引用
收藏
页码：391 / 396
页数：6
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