CT, RECIST, and malignant pleural mesothelioma

被引：28
|
作者：
Nowak, AK
机构：
[1] Univ Western Australia, Dept Med & Pharmacol, Nedlands, WA 6009, Australia
[2] Sir Charles Gairdiner Hosp, Dept Med Oncol, Nedlands, WA 6009, Australia
来源：
LUNG CANCER | 2005年 / 49卷
关键词：
malignant; mesothelioma; RECIST; tumour measurement; uni-dimensional;
D O I：
10.1016/j.lungcan.2005.03.030
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
The unique growth pattern of malignant pleural. mesothelioma (MPM) presents challenges for clinical investigators assessing tumour response to treatment. Assessment of response is an important surrogate for patient benefit, particularly in phase II clinical trials. Neither the previous WHO criteria nor the more recent RECIST criteria are well suited to tumour measurement in this disease. This paper discusses uni-dimensional measurement of tumour response in pleural mesothelioma, and the development and validation of the modified RECIST criteria for MPM, which attempt to overcome some of the shortcomings of the RECIST criteria in this setting. (c) 2005 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码：S37 / S40
页数：4
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