TOPLINE RESULTS FROM THE ALPINE 2/3 STUDY: A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, MULTICENTER, PHASE 2b TRIAL EVALUATING 3 DOSES OF THE FGF19 ANALOGUE ALDAFERMIN ON LIVER HISTOLOGY IN PATIENTS WITH NONALCOHOLIC STEATOHEPATITIS AND STAGE 2 OR 3 FIBROSIS

被引：0

作者：

Harrison, Stephen A. ^{[1
]}

Abdelmalek, Manal F. ^{[2
]}

Neff, Guy W. ^{[3
]}

Gunn, Nadege ^{[1
]}

Guy, Cynthia D. ^{[2
]}

Alkhouri, Naim ^{[4
]}

Bashir, Mustafa ^{[2
]}

Freilich, Bradley ^{[5
]}

Almeda, Jose ^{[6
]}

Knapple, Whitfield ^{[7
]}

Kohli, Anita ^{[4
]}

Khazanchi, Arun ^{[8
]}

Sheikh, Muhammad Y. ^{[9
]}

Leibowitz, Mark ^{[10
]}

Hogan, Reed ^{[11
]}

White, Judith ^{[12
]}

Kayali, Zeid ^{[13
]}

Rinella, Mary E. ^{[14
]}

Siddiqui, Mohammad S. ^{[15
]}

Kipnes, Mark ^{[16
]}

Moussa, Sam E. ^{[17
]}

Ortiz-Lasanta, Grisell ^{[18
]}

Poulos, John ^{[19
]}

Younes, Ziad ^{[20
]}

Bansal, Meena B. ^{[21
]}

Baum, Seth J. ^{[22
]}

Borg, Brian ^{[23
]}

Ruane, Peter J. ^{[24
]}

White, Alexander ^{[25
]}

Merkes, Kevin ^{[26
]}

Rashmee, Patil ^{[27
]}

Thuluvath, Paul J. ^{[28
,29
]}

Gottwald, Mildred ^{[30
]}

Khan, Mujib ^{[30
]}

Chen, Charles ^{[30
]}

Yan, Andrew Z. ^{[30
]}

Melchor-Khan, Liza ^{[30
]}

Chang, William ^{[30
]}

DePaoli, Alex ^{[30
]}

Ling, Lei ^{[30
]}

Lieu, Hsiao ^{[30
]}

机构：

[1] Pinnacle Clin Res, San Antonio, TX USA

[2] Duke Univ, Durham, NC USA

[3] Covenant Res & Clin, LLC, Sarasota, FL USA

[4] Arizona Liver Hlth, Chandler, AZ USA

[5] Kansas City Res Inst, Kansas City, MO USA

[6] Doctors Hosp Renaissance, Edinburg, TX USA

[7] Arkansas Gastroenterol, Hot Springs, AR USA

[8] Florida Res Inst, Bradenton, FL USA

[9] Fresno Clin Res Ctr, Fresno, CA USA

[10] Natl Res Inst, Delhi, NY USA

[11] GI Assoc & Endoscopy Ctr, Wausau, WI USA

[12] Bioclin Res, Princeton, NJ USA

[13] Inland Empire Liver Fdn, Rialto, CA USA

[14] Northwestern Univ, Evanston, IL USA

[15] Virginia Commonwealth Univ, Dept Internal Med, Div Gastroenterol Hepatol & Nutr, Richmond, VA USA

[16] Diabet & Glandular Dis Clin, San Antonio, TX USA

[17] Adobe Clin Res, Tucson, AZ USA

[18] Fdn Invest, San Juan, PR USA

[19] Cumberland Res Assoc, Cumberland, MD USA

[20] Gastro One, Germantown, TN USA

[21] Icahn Sch Med Mt Sinai, Dept Med, Div Liver Dis, New York, NY 10029 USA

[22] Excel Med Clin Trials, Boca Raton, FL USA

[23] Southern Therapy & Adv Res, Madison, NJ USA

[24] Ruane Clinical Res Grp Inc, Los Angeles, CA USA

[25] Progress Med Res, Port Orange, FL USA

[26] Alliance Clin Res, Alliance, OH USA

[27] South Texas Res Inst, Edinburg, TX USA

[28] Mercy Med Ctr, Baltimore, MD USA

[29] Univ Maryland, Sch Med, Baltimore, MD USA

[30] Ngm Biopharmaceut, San Francisco, CA USA

来源：

HEPATOLOGY | 2021年 / 74卷

关键词：

D O I：

暂无

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

引用

页码：5A / 6A

页数：2

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