Holmium:YAG lithotripsy:: Photothermal mechanism converts uric acid calculi to cyanide

被引：32

作者：

Teichman, JMH

Vassar, GJ

Glickman, RD

Beserra, CM

Cina, SJ

Thompson, IM

机构：

[1] Univ Texas, Hlth Sci Ctr, Div Urol, San Antonio, TX 78284 USA

[2] Univ Texas, Hlth Sci Ctr, Brooke Army Med Ctr, Dept Ophthalmol, San Antonio, TX USA

[3] Wilford Hall USAF Med Ctr, Dept Pathol, Lackland AFB, TX 78236 USA

[4] Off Epidemiol & Toxicol, Brooks AFB, TX USA

来源：

JOURNAL OF UROLOGY | 1998年 / 160卷 / 02期

关键词：

holmium; lithotripsy; laser; uric acid; calculi;

D O I：

10.1016/S0022-5347(01)62883-0

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Purpose: Holmium:YAG lithotripsy fragments stones through a photothermal mechanism. Uric acid when heated is known to be converted into cyanide, We test the hypothesis that holmium: YAG lithotripsy of uric acid calculi produces cyanide. Materials and Methods: Human calculi of known uric acid composition were irradiated with holmium:YAG energy in water. Stones received a total holmium:YAG energy of 0 (control), 0.1, 0.25, 0.5, 0.75, 1.0 or 1.25 kJ. The water in which lithotripsy was performed was analyzed for cyanide concentration. A graph was constructed to relate holmium:YAG energy to cyanide production. Results: Holmium:YAG lithotripsy of uric acid calculi in vitro produced cyanide consistently. Cyanide production correlated with total holmium:YAG energy (p <0.001). Conclusions: Holmium:YAG lithotripsy of uric acid calculi risks production of cyanide. This study raises significant safety issues.

引用

页码：320 / 324

页数：5

共 48 条

[1] Holmium:YAG lithotripsy of uric acid calculi
Teichman, JMH
Champion, PC
Wollin, TA
Denstedt, JD
[J]. JOURNAL OF UROLOGY, 1998, 160 (06): : 2130 - 2132
[2] Fragmentation of uric acid calculi with the holmium: YAG laser produces cyanide
Zagone, RL
Waldmann, TM
Conlin, MJ
[J]. LASERS IN SURGERY AND MEDICINE, 2002, 31 (04) : 230 - 232
[3] Holmium:YAG lithotripsy:: Photothermal mechanism
Vassar, GJ
Chan, KF
Teichman, JMH
Glickman, RD
Weintraub, ST
Pfefer, TJ
Welch, AJ
[J]. JOURNAL OF ENDOUROLOGY, 1999, 13 (03) : 181 - 190
[4] Photothermal ablation is the primary mechanism in Holmium:YAG laser lithotripsy of urinary calculi
Glickman, RD
Teichman, JMH
Corbin, NS
Vassar, GJ
Weintraub, SE
Chan, KF
Welch, AJ
[J]. 1999 INTERNATIONAL CONFERENCE ON BIOMEDICAL OPTICS (BMO'99), 1999, 3863 : 376 - 384
[5] Photothermal laser lithotripsy of uric acid calculi: Clinical assessment of the effects of cyanide production
Teichman, JMH
Champion, PC
Glickman, RD
Wollin, TA
Denstedt, JD
[J]. LASERS IN SURGERY: ADVANCED CHARACTERIZATION, THERAPEUTICS, AND SYSTEMS IX, PROCEEDINGS OF, 1999, 3590 : 210 - 214
[6] Holmium:YAG laser lithotripsy:: A dominant photothermal ablative mechanism with chemical decomposition of urinary calculi
Chan, KF
Vassar, GJ
Pfefer, TJ
Teichman, JWH
Glickman, RD
Weintraub, ST
Welch, AJ
[J]. LASERS IN SURGERY AND MEDICINE, 1999, 25 (01) : 22 - 37
[7] Further characterization of photothermal breakdown products of uric acid stones following Holmium:YAG laser lithotripsy
Glickman, RD
Weintraub, SE
Kumar, N
Corbin, NS
Lesani, O
Teichman, JMH
[J]. LASER-TISSUE INTERACTION XI: PHOTOCHEMICAL, PHOTOTHERMAL, AND PHOTOMECHANICAL, 2000, 3914 : 144 - 152
[8] Holmium:YAG laser lithotripsy of intrahepatic biliary calculi
Tarman, GJ
Lenert, JT
Hall, L
Kane, CJ
[J]. JOURNAL OF ENDOUROLOGY, 1999, 13 (05) : 381 - 383
[9] Holmium:YAG lithotripsy for large renal and bladder calculi:: strategies for efficient lithotripsy
Teichman, JMH
[J]. JOURNAL OF ENDOUROLOGY, 1999, 13 (07) : 477 - 480
[10] Clinical experience with holmium:YAG laser lithotripsy of ureteral calculi
Yiu, MK
Liu, PL
Yiu, TF
Chan, AYT
[J]. LASERS IN SURGERY AND MEDICINE, 1996, 19 (01) : 103 - 106

← 1 2 3 4 5 →