Separation of positional isomers of chlorophenols by reverse phase HPLC

被引:0
|
作者
Huang, GL [1 ]
Zhang, WH [1 ]
Zhang, ZR [1 ]
机构
[1] TIANJIN MED UNIV HOSP,INST NEUROL,TIANJIN,PEOPLES R CHINA
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中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
With RP-HPLC, an optimum gradient elution was achieved for separation of 15 chlorophenol positional isomers. Recoveries were satisfactory. The lowest detection limit is 5 X 10(-10)g. This method is suitable for determining these substances in environmental samples. The relationship between Capacity Factor (k'), Total Surface Area (TSA), and Molecular Connectivity Index ((1)x, (1)x(v)) of chlorophenol congeners was studied, which is reported here for the first time.
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页码:899 / 909
页数:11
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