Real-world use of inhaled treprostinil for lung disease-pulmonary hypertension: A protocol for patient evaluation and prescribing

被引：3
|
作者：
Johnson, Shelsey W. [1 ,2 ]
Finlay, Lauren [3 ]
Mathai, Stephen C. [4 ,5 ]
Goldstein, Ronald H. [1 ,2 ]
Maron, Bradley A. [1 ,6 ,7 ]
机构：
[1] VA Boston Healthcare Syst, Dept Pulm Allergy Sleep & Crit Care Med, 77 Ave Louis Pasteur,NRB 0630-N, Boston, MA 02115 USA
[2] Boston Univ, Sch Med, Ctr Pulm, Div Pulm Allergy Sleep & Crit Care, Boston, MA 02215 USA
[3] VA Boston Healthcare Syst, Dept Pharm, Boston, MA USA
[4] Johns Hopkins Univ, Dept Pulm & Crit Care Med, Baltimore, MD USA
[5] Johns Hopkins Sch Med, Baltimore, MD USA
[6] Brigham & Womens Hosp, Div Cardiovasc Med, 75 Francis St, Boston, MA 02115 USA
[7] Harvard Med Sch, Boston, MA 02115 USA
来源：
PULMONARY CIRCULATION | 2022年 / 12卷 / 03期
关键词：
Group 3 pulmonary hypertension; inhaled treprostinil; interstitial lung disease; pulmonary hypertension; ARTERIAL-HYPERTENSION; THERAPY; CAPACITY; OUTCOMES;
D O I：
10.1002/pul2.12126
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Inhaled treprostinil was approved recently for interstitial lung disease-pulmonary hypertension; however, efficacy in "real-world" populations is not known. We designed a protocol and report our experience evaluating 10 patients referred for therapy. Misdiagnosis at presentation was common; ultimately, three patients (30%) were prescribed drug. This protocol offers an opportunity to standardize longitudinal assessment of inhaled treprostinil in clinical practice.
引用
收藏
页数：7
相关论文
共 50 条
  • [1] Inhaled Treprostinil in Pulmonary Hypertension Associated with Lung Disease
    Faria-Urbina, Mariana
    Oliveira, Rudolf K. F.
    Agarwal, Manyoo
    Waxman, Aaron B.
    [J]. LUNG, 2018, 196 (02) : 139 - 146
  • [2] Inhaled Treprostinil in Pulmonary Hypertension Associated with Lung Disease
    Mariana Faria-Urbina
    Rudolf K. F. Oliveira
    Manyoo Agarwal
    Aaron B. Waxman
    [J]. Lung, 2018, 196 : 139 - 146
  • [3] Real-world evidence of subcutaneous treprostinil use in pulmonary arterial hypertension in Argentina
    Lescano, Adrian
    Giacommi, Guillermo
    Botta, Cristian E.
    Soricetti, Julieta
    Rodriguez, Manuel
    Mielles, Paul Vargas
    Diez, Fabian
    [J]. THERAPEUTIC ADVANCES IN RESPIRATORY DISEASE, 2022, 16
  • [4] Real-world evidence of subcutaneous treprostinil use in pulmonary arterial hypertension in Argentina
    Lescano, Adrian
    Giacommi, Guillermo
    Botta, Cristian E.
    Soricetti, Julieta
    Rodriguez, Manuel
    Vargas Mielles, Paul
    Diez, Fabian
    [J]. THERAPEUTIC ADVANCES IN RESPIRATORY DISEASE, 2022, 16
  • [5] Real-world evidence of subcutaneous treprostinil use in pulmonary arterial hypertension in Argentina
    Lescano, Adrian
    Giacommi, Guillermo
    Botta, Cristian E.
    Soricetti, Julieta
    Rodriguez, Manuel
    Mielles, Paul Vargas
    Diez, Fabian
    [J]. THERAPEUTIC ADVANCES IN RESPIRATORY DISEASE, 2022, 16
  • [6] Inhaled Treprostinil in Pulmonary Hypertension Due to Interstitial Lung Disease
    Waxman, Aaron
    Restrepo-Jaramillo, Ricardo
    Thenappan, Thenappan
    Ravichandran, Ashwin
    Engel, Peter
    Bajwa, Abubakr
    Allen, Roblee
    Feldman, Jeremy
    Argula, Rahul
    Smith, Peter
    Rollins, Kristan
    Deng, Chunqin
    Peterson, Leigh
    Bell, Heidi
    Tapson, Victor
    Nathan, Steven D.
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2021, 384 (04): : 325 - 334
  • [7] Inhaled Treprostinil in Pulmonary Hypertension in the Context of Interstitial Lung Disease: A Success, Finally
    Behr, Juergen
    [J]. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2022, 205 (02) : 144 - 146
  • [8] COMPARISON OF EFFECTS OF INHALED TREPROSTINIL ON LUNG FUNCTION IN PATIENTS WITH PULMONARY HYPERTENSION ASSOCIATED WITH INTERSTITIAL LUNG DISEASE AND PULMONARY ARTERIAL HYPERTENSION
    Nathan, Steven
    Tapson, Victor
    Ramani, Gautam
    Medarov, Boris
    Levine, Deborah
    Burger, Charles
    El-Kersh, Karim
    Shen, Eric
    Rao, Youlan
    Smith, Peter
    Waxman, Aaron
    [J]. CHEST, 2021, 160 (04) : 2244A - 2246A
  • [9] Interstitial lung disease with pulmonary hypertension and the potential for inhaled Treprostinil: A single centre perspective
    Ramjug, S.
    Hayton, C.
    Rivera-Ortega, P.
    Leonard, C.
    Morris, H.
    Zakis, K.
    Swale, J.
    Garfoot, T.
    Newman, K.
    Avram, C.
    Blaikley, J.
    Chaudhuri, N.
    [J]. EUROPEAN RESPIRATORY JOURNAL, 2022, 60
  • [10] Interstitial Lung Disease and Pulmonary Hypertension in Systemic Sclerosis: A Real-World Experience
    Sangani, R.
    Schoenberg, N.
    Chen, C.
    Dukes, K.
    Klings, E. S.
    [J]. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2019, 199
12345