Study The Pharmacological Activity Of Methanolic Extract Of Cercis Siliquastrum L. Leaves On Animal Model

被引：0

作者：

Al Ali, Asmaa M. H. ^{[1
]}

Mounce, Faten S. ^{[1
]}

Neamah, Nadheerah F. ^{[1
]}

机构：

[1] Univ Basrah, Coll Pharm, Pharmacol & Toxicol Dept, Basrah, Iraq

来源：

JOURNAL OF PHARMACEUTICAL NEGATIVE RESULTS | 2022年 / 13卷

关键词：

Analgesic; Cercis siliquastrum; Anti-inflammatory; Gastrointestinal; Antidepressant activity;

D O I：

10.47750/pnr.2022.13.S02.35

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Cercis siliquastrum (Judas tree) is a commonly used traditional medicine in Iraq with drug discovery potential. The aim of this study was to investigate the in vivo acutes toxicity, analgesic activity by acetic acid induced writhing model, Anti-inflammatory by Carrageenan induced paw edema method, gastrointestinal tract (GIT) motility by charcoal meal protocol, antidepressant activity by using forced swimming test (FST) model of methanolic extract Cercis siliquastrum L. leaves (MECSL). Differenet concentration of MECSL curde extract was used (50 mg/kg, 150 mg/kg, 300 mg/kg. The results revealed that Cercis siliquastrum methanloic extract is dose dependent. Crude MECSL extract proved a strong analgesic, anti-inflammatory, and properties.

引用

页码：250 / 254

页数：5

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