7α-Alkoxyestra-1,3,5(10)-trienes

被引：2

作者：

Yasuda, Takurni ^{[1
]}

Shima, Yuji ^{[1
]}

Ideta, Keiko ^{[2
]}

Oliveira, Cristina Das Neves ^{[3
]}

Thiemann, Thies ^{[1
]}

机构：

[1] Kyushu Univ, Interdisciplinary Grad Sch Engn Sci, Kasuga, Fukuoka 8168580, Japan

[2] Kyushu Univ, Inst Mat Chem & Engn, Kasuga, Fukuoka 8168580, Japan

[3] Inst Tecnol & Ncul, P-2686953 Sacavem, Portugal

来源：

JOURNAL OF CHEMICAL RESEARCH | 2008年 / 01期

关键词：

steroids; estradiol; ethers;

D O I：

10.3184/030823408X287140

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

alpha-Alkoxyestradiols were prepared through LiAlH4 reduction of a suitably protected 6 alpha,7 alpha-epoxyestra-1,3,5(10)trien-3-ol-17-one, alkylation of the resultant 7 alpha-hydroxyestra-1,3,5(10)-trien-3-ol-17-one derivative and subsequent transformation of the C17 functionality.

引用

页码：32 / 37

页数：6

共 50 条

[1] Synthesis and biological evaluation of 17β-alkoxyestra-1,3,5(10)-trienes as potential neuroprotectants against oxidative stress
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[2] SYNTHESIS OF 3-FLUOROESTRA-1,3,5(10)-TRIENES
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[3] 3-DEOXY-16-HALOESTRA-1,3,5(10)-TRIENES
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[5] PREPARATION OF STEROIDAL 3-HALOANDROSTA-1,3,5-TRIENES + 1-HALO-4METHYLESTRA-1,3,5(10)-TRIENES
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[6] A NOVEL ROUTE TO 3-ALKYLATED ESTRA-1,3,5(10)-TRIENES
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[7] CERIUM(IV) OXIDATION OF 4-METHYLOESTRA-1,3,5(10)-TRIENES
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[8] ESTROGENIC ACTIVITIES OF SOME 3-ALKOXYESTRA-1,3,5(10)-TRIEN-17BETA-OLS
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[10] POSTCOITAL ANTIFERTILITY ACTIVITY OF 17-BETA-CARBAMOYLOXYESTRA-1,3,5(10)-TRIENES
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