Saccadic eye movements in Parkinson's disease

被引:24
|
作者
Srivastava, Anshul [1 ]
Sharma, Ratna [1 ]
Sood, Sanjay K. [3 ]
Shukla, Garima [2 ]
Goyal, Vinay [2 ]
Behari, Madhuri [2 ]
机构
[1] All India Inst Med Sci, Dept Physiol, New Delhi 110029, India
[2] All India Inst Med Sci, Dept Neurol, New Delhi 110029, India
[3] RAKMHSU, RAK Coll Med, Dept Physiol, Ras Al Khaymah, U Arab Emirates
关键词
Parkinson's disease; saccadic eye movements; deep brain stimulation; eye movement paradigm; MEMORY-GUIDED SACCADES; DEEP BRAIN-STIMULATION; NIGRA PARS RETICULATA; SUPERIOR COLLICULUS; CORTICAL CONTROL; BASAL GANGLIA; OCULAR MOTOR; REFLEXIVE SACCADES; VOLUNTARY SACCADES; MONKEY;
D O I
10.4103/0301-4738.133482
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
This review focuses on saccadic eye movement research in Parkinson's disease (PD) patients. Results from various studies related to Parkinson disease and saccades have been discussed in terms of various saccadic parameters like latency, amplitude, velocity and gain. Neural circuitry of saccadic eye movements and cognitive processes and it's relation with altered saccadic performance in Parkinson disease has been discussed here. This article also covers various research paradigms commonly used to study saccades. Effects of medication on saccadic parameters in PD patients have also been discussed along with the effects of deep brain stimulation of subthalamic nucleus on saccadic performance in PD patients. Literature review was done using online Pubmed search engine and National Medical Library.
引用
收藏
页码:538 / 544
页数:7
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