Airway microbial metagenomics

被引：8
|
作者：
Pienkowska, Katarzyna [1 ]
Wiehlmann, Lutz [1 ,2 ]
Tuemmler, Burkhard [1 ,3 ]
机构：
[1] Hannover Med Sch, Clin Pediat Pneumol Allergol & Neonatol, Clin Res Grp, Carl Neuberg Str 1, D-30625 Hannover, Germany
[2] Hannover Med Sch, Core Unit Genom, Carl Neuberg Str 1, D-30625 Hannover, Germany
[3] Hannover Med Sch, German Ctr Lung Res, Biomed Res Endstage & Obstruct Lung Dis Hannover, Carl Neuberg Str 1, D-30625 Hannover, Germany
来源：
MICROBES AND INFECTION | 2018年 / 20卷 / 9-10期
关键词：
Metagenome; Respiratory tract; Cystic fibrosis; Chronic obstructive pulmonary disease; DE-NOVO ASSEMBLER; IDBA;
D O I：
10.1016/j.micinf.2017.12.002
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
High-throughput untargeted metagenome sequencing provides information about the composition of the microbial communities of viruses, bacteria, archaea and unicellular eukaryotes in the habitat of interest. This review outlines the sampling, processing, sequencing and bioinformatic analysis of secretions of the respiratory tract and summarizes our current knowledge of the upper and lower human airways metagenome in health and disease. (C) 2017 Institut Pasteur. Published by Elsevier Masson SAS. All rights reserved.
引用
收藏
页码：536 / 542
页数：7
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