Diabetes and endometrial cancer: effect modification by body weight, physical activity and hypertension

被引:42
|
作者
Lucenteforte, E.
Bosetti, C.
Talamini, R.
Montella, M.
Zucchetto, A.
Pelucchi, C.
Franceschi, S.
Negri, E.
Levi, F.
La Vecchia, C.
机构
[1] Ist Ric Farmacol Mario Negri, Milan, Italy
[2] Ctr Riferimento Oncol, Unita Epidemiol & Biostat, Aviano, Italy
[3] Ist Nazl Tumori Fdn Giovanni Pascale, Epidemiol Unit, Naples, Italy
[4] Int Agcy Res Canc, F-69372 Lyon, France
[5] Univ Lausanne, Inst Social & Prevent Med, Unit Epidemiol Canc, Lausanne, Switzerland
[6] Univ Milan, Ist Stat Med & Biometria, Milan, Italy
关键词
case-control study; endometrial cancer; diabetes; body mass index; physical activity; hypertension;
D O I
10.1038/sj.bjc.6603933
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Among 777 endometrial cancer cases and 1550 controls from Italy and Switzerland, odds ratio was 1.7 ( 95% confidence interval: 1.2 - 2.5) for diabetes, and 5.1 for obese diabetic women as compared with non-obese non-diabetic ones. Diabetes shows a supramultiplicative effect with body mass index, but not with physical activity or hypertension.
引用
收藏
页码:995 / 998
页数:4
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