Preclinical target validation using patient-derived cells

被引：37
|
作者：
Edwards, Aled M. [1 ]
Arrowsmith, Cheryl H. [1 ]
Bountra, Chas [2 ]
Bunnage, Mark E. [3 ]
Feldmann, Marc [4 ]
Knight, Julian C. [5 ]
Patel, Dhavalkumar D. [6 ]
Prinos, Panagiotis [1 ]
Taylor, Michael D. [7 ]
Sundstrom, Michael [8 ,9 ]
机构：
[1] Univ Toronto, Struct Genom Consortium, Toronto, ON M5G 1L7, Canada
[2] Univ Oxford, Nuffield Dept Clin Med, SGC, Oxford OX3 7LD, England
[3] Pfizer Worldwide Res & Dev, Worldwide Med Chem, Cambridge, MA 02139 USA
[4] Univ Oxford, Kennedy Inst Rheumatol, Headington OX3 7FY, England
[5] Univ Oxford, Wellcome Trust Ctr Human Genet, Oxford OX3 7BN, England
[6] Novartis Inst BioMed Res, CH-4002 Basel, Switzerland
[7] Hosp Sick Children, Program Dev & Stem Cell Biol, Div Neurosurg, Toronto, ON M5G 1X8, Canada
[8] Karolinska Univ Hosp, Dept Med, SGC, S-17176 Stockholm, Sweden
[9] Karolinska Inst, S-17176 Stockholm, Sweden
来源：
NATURE REVIEWS DRUG DISCOVERY | 2015年 / 14卷 / 03期
关键词：
D O I：
10.1038/nrd4565
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
The Structural Genomics Consortium (SGC) and its clinical, industry and disease-foundation partners are launching open-source preclinical translational medicine studies.
引用
收藏
页码：149 / 150
页数：2
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