Prevalence of Depression and Anxiety in Nurses during the First Eleven Months of the COVID-19 Pandemic: A Systematic Review and Meta-Analysis

The high risk of coronavirus (COVID-19) infection can increase the physical and psychological strain on nurses in professional practice, which can lead to mental health problems. The purpose of this systematic review and meta-analysis is to establish and estimate the combined incidence of depression and anxiety among nurses during the COVID-19 pandemic using standard measurement tools. A systematic search of the electronic databases PubMed, Web of Science, and SCOPUS was carried out to identify cross-sectional studies in the period from 3 March 2020 to 18 February 2021. Two reviewers independently and critically evaluated the studies which have been included, using the Agency for Healthcare Research and Quality checklist. We have identified twenty-three studies (n = 44,165) from nine countries. The combined incidence of depression among nurses was 22% (95% CI 0.15-0.30, I-2 = 99.71%), and anxiety symptoms 29% (95%CI 0.18-0.40, I-2 = 99.92%). No significant difference was observed in the percentage of depression and anxiety between the study subjects working on the frontlines vs. those in a mixed group (those working on the frontlines and behind the lines). This meta-analysis shows that over one-fifth of nurses in professional practice during the COVID-19 epidemic suffer from depression disorders, and almost one-third experience anxiety symptoms. This underscores the importance of providing comprehensive psychological support strategies for nurses working in pandemic conditions. Further longitudinal research is necessary to assess the severity of mental health symptoms related to the COVID-19 epidemic factor.